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1. WO2000040204 - METHODS FOR TREATING CYSTIC FIBROSIS

Publication Number WO/2000/040204
Publication Date 13.07.2000
International Application No. PCT/US2000/000480
International Filing Date 07.01.2000
Chapter 2 Demand Filed 02.08.2000
IPC
A61K 38/00 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
38Medicinal preparations containing peptides
C07K 14/47 2006.01
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
14Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
435from animals; from humans
46from vertebrates
47from mammals
CPC
A61K 38/00
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
38Medicinal preparations containing peptides
C07K 14/4723
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
14Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
435from animals; from humans
46from vertebrates
47from mammals
4701not used
4723Cationic antimicrobial peptides, e.g. defensins
Applicants
  • PERIODONTIX, INC. [US/US]; 313 Pleasant Street Watertown, MA 02472, US
Inventors
  • SPACCIAPOLI, Peter; US
  • ROTHSTEIN, David, M.; US
  • FRIDEN, Phillip, M.; US
Agents
  • CLARK, Paul, T.; Clark & Elbing LLP 176 Federal Street Boston, MA 02110-2214, US
Priority Data
09/226,66608.01.1999US
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) METHODS FOR TREATING CYSTIC FIBROSIS
(FR) METHODES DE TRAITEMENT DE LA FIBROSE KYSTIQUE
Abstract
(EN)
Methods for treating cystic fibrosis in a mammal that include administering to the mammal an effective amount of a histatin, a histatin fragment, or a histatin-related peptide are disclosed. The histatin, histatin fragment, or histatin-related peptide exhibits antibacterial activity against P. aeruginosa (Figure 3).
(FR)
L'invention concerne des méthodes de traitement de la fibrose kystique chez les mammifères, consistant à administrer une dose efficace d'histatine, d'un fragment d'histatine, ou d'un peptide apparenté à l'histatine.
Latest bibliographic data on file with the International Bureau