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1. WO2000039545 - FLUORESCENCE MEASURING DEVICE

Publication Number WO/2000/039545
Publication Date 06.07.2000
International Application No. PCT/EP1999/010311
International Filing Date 22.12.1999
Chapter 2 Demand Filed 19.07.2000
IPC
G01J 3/12 2006.01
GPHYSICS
01MEASURING; TESTING
JMEASUREMENT OF INTENSITY, VELOCITY, SPECTRAL CONTENT, POLARISATION, PHASE OR PULSE CHARACTERISTICS OF INFRA-RED, VISIBLE OR ULTRA-VIOLET LIGHT; COLORIMETRY; RADIATION PYROMETRY
3Spectrometry; Spectrophotometry; Monochromators; Measuring colours
12Generating the spectrum; Monochromators
G01J 3/44 2006.01
GPHYSICS
01MEASURING; TESTING
JMEASUREMENT OF INTENSITY, VELOCITY, SPECTRAL CONTENT, POLARISATION, PHASE OR PULSE CHARACTERISTICS OF INFRA-RED, VISIBLE OR ULTRA-VIOLET LIGHT; COLORIMETRY; RADIATION PYROMETRY
3Spectrometry; Spectrophotometry; Monochromators; Measuring colours
28Investigating the spectrum
44Raman spectrometry; Scattering spectrometry
G01N 21/64 2006.01
GPHYSICS
01MEASURING; TESTING
NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
21Investigating or analysing materials by the use of optical means, i.e. using infra-red, visible or ultra-violet light
62Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
63optically excited
64Fluorescence; Phosphorescence
G02F 1/11 2006.01
GPHYSICS
02OPTICS
FDEVICES OR ARRANGEMENTS, THE OPTICAL OPERATION OF WHICH IS MODIFIED BY CHANGING THE OPTICAL PROPERTIES OF THE MEDIUM OF THE DEVICES OR ARRANGEMENTS FOR THE CONTROL OF THE INTENSITY, COLOUR, PHASE, POLARISATION OR DIRECTION OF LIGHT, e.g. SWITCHING, GATING, MODULATING OR DEMODULATING; TECHNIQUES OR PROCEDURES FOR THE OPERATION THEREOF; FREQUENCY-CHANGING; NON-LINEAR OPTICS; OPTICAL LOGIC ELEMENTS; OPTICAL ANALOGUE/DIGITAL CONVERTERS
1Devices or arrangements for the control of the intensity, colour, phase, polarisation or direction of light arriving from an independent light source, e.g. switching, gating or modulating; Non-linear optics
01for the control of the intensity, phase, polarisation or colour
11based on acousto-optical elements, e.g. using variable diffraction by sound or like mechanical waves
CPC
G01J 3/1256
GPHYSICS
01MEASURING; TESTING
JMEASUREMENT OF INTENSITY, VELOCITY, SPECTRAL CONTENT, POLARISATION, PHASE OR PULSE CHARACTERISTICS OF INFRA-RED, VISIBLE OR ULTRA-VIOLET LIGHT; COLORIMETRY; RADIATION PYROMETRY
3Spectrometry; Spectrophotometry; Monochromators; Measuring colours
12Generating the spectrum; Monochromators
1256using acousto-optic tunable filter;
G01J 3/4406
GPHYSICS
01MEASURING; TESTING
JMEASUREMENT OF INTENSITY, VELOCITY, SPECTRAL CONTENT, POLARISATION, PHASE OR PULSE CHARACTERISTICS OF INFRA-RED, VISIBLE OR ULTRA-VIOLET LIGHT; COLORIMETRY; RADIATION PYROMETRY
3Spectrometry; Spectrophotometry; Monochromators; Measuring colours
28Investigating the spectrum
44Raman spectrometry; Scattering spectrometry ; ; Fluorescence spectrometry
4406Fluorescence spectrometry
G01N 21/645
GPHYSICS
01MEASURING; TESTING
NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
21Investigating or analysing materials by the use of optical means, i.e. using infra-red, visible or ultra-violet light
62Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
63optically excited
64Fluorescence; Phosphorescence
645Specially adapted constructive features of fluorimeters
G02F 1/11
GPHYSICS
02OPTICS
FDEVICES OR ARRANGEMENTS, THE OPTICAL OPERATION OF WHICH IS MODIFIED BY CHANGING THE OPTICAL PROPERTIES OF THE MEDIUM OF THE DEVICES OR ARRANGEMENTS FOR THE CONTROL OF THE INTENSITY, COLOUR, PHASE, POLARISATION OR DIRECTION OF LIGHT, e.g. SWITCHING, GATING, MODULATING OR DEMODULATING; TECHNIQUES OR PROCEDURES FOR THE OPERATION THEREOF; FREQUENCY-CHANGING; NON-LINEAR OPTICS; OPTICAL LOGIC ELEMENTS; OPTICAL ANALOGUE/DIGITAL CONVERTERS
1Devices or arrangements for the control of the intensity, colour, phase, polarisation or direction of light arriving from an independent light source, e.g. switching, gating, or modulating; Non-linear optics
01for the control of the intensity, phase, polarisation or colour 
11based on acousto-optical elements, e.g. using variable diffraction by sound or like mechanical waves
Applicants
  • AMERSHAM PHARMACIA BIOTECH AB [SE/SE]; S-751 84 Uppsala, SE (AllExceptUS)
  • TORMOD, Stig [SE/SE]; SE (UsOnly)
Inventors
  • TORMOD, Stig; SE
Agents
  • ROLLINS, Anthony, John; Nycomed Amersham plc Amersham Laboratories White Lion Road Amersham Bucks HP7 9LL, GB
Priority Data
9804551-128.12.1998SE
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) FLUORESCENCE MEASURING DEVICE
(FR) DISPOSITIF DE MESURE DE LA FLURORESCENCE
Abstract
(EN)
A fluorescence measuring unit comprising a monochromatic light source (13), a detector unit (23a, 23b), an excitation beam (13a) going from the light source (13) to the spot (18), an emission beam going from the spot (18) to the detector unit (23a, 23b) and an acousto optic tuneable filter (AOTF) (12), arranged in a non-collinear mode, and such that the excitation beam path and the emission beam path coincide but propagate in the AOTF in opposite directions. An arrangement comprising two laser sources (27) defining two beam paths leading to a common beam path (31) with the features that: a) said laser sources have polarisation planes perpendicular to each other and b) a non-collinear AOTF (29) is placed in the conjunction of said two beam paths and oriented such that, when tuned to the respective wavelength of the laser light from the respective laser source, the laser light from the two sources will pass and exit the second AOTF (29) in one and the same beam path (31).
(FR)
L'invention porte sur une unité de mesure de la fluorescence qui comprend une source (13) lumineuse monochromatique, une unité de détection (23a, 23b), un faisceau (13a) d'excitation allant de la source (13) lumineuse au point (18), un faisceau d'émission allant du point (18) à l'unité de détection (23a, 23b) et un filtre (12) accordable acousto-optique (AOTF). Cette unité de mesure est agencée selon un mode non colinéaire de sorte que le trajet du faisceau d'excitation et le trajet du faisceau d'émission coïncident et se propagent dans le filtre dans des directions opposées. Le dispositif de cette invention comprend deux sources (27) laser formant deux trajets de faisceau aboutissant à un trajet (31) commun. Cette unité se caractérise en ce que: a) les sources lasers possèdent des plans de polarisation perpendiculaires, et b) un filtre AOTF (29) non colinéaire est placé dans l'intersection des deux trajets du faisceau et orienté de sorte que, lorsqu'il est accordé par rapport à la longueur d'onde respective de la lumière laser provenant de chaque source laser, la lumière laser passe dans le second filtre (29) AOTF et sorte de celui-ci sous forme d'un même et unique trajet (31).
Also published as
US09869633
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