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1. WO2000039280 - LEUKOCYTE-DERIVED INTERFERON PREPARATIONS

Publication Number WO/2000/039280
Publication Date 06.07.2000
International Application No. PCT/US1999/031198
International Filing Date 29.12.1999
Chapter 2 Demand Filed 28.07.2000
IPC
A61K 38/00 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
38Medicinal preparations containing peptides
C07K 14/56 2006.01
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
14Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
435from animals; from humans
52Cytokines; Lymphokines; Interferons
555Interferons (IFN)
56IFN-alpha
CPC
A61K 38/00
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
38Medicinal preparations containing peptides
C07K 14/56
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
14Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
435from animals; from humans
52Cytokines; Lymphokines; Interferons
555Interferons [IFN]
56IFN-alpha
Y02A 50/463
YSECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
50in human health protection
30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
46Medical treatment of waterborne diseases characterized by the agent
462The waterborne disease being caused by a virus
463the virus being the Hepatitis A virus [HAV]
Applicants
  • VIRAGEN, INC. [US/US]; Suite 100 865 S.W. 78th Avenue Plantation, FL 33324, US
Inventors
  • MORRIS, Joseph, P.; US
  • NGUYEN, Duy; US
  • KAPPELMAN, James; US
  • MCCABE, Mead, M.; US
  • POTTER, Michael, D.; US
  • ZIAI, M., Reza; US
  • FELDMAN, Stephen; US
  • HARTMAN, Hipolito; US
Agents
  • GALE, James, A. ; Feldman, Gale & Weber, P.A. Miami Center, 19th Floor 201 South Biscayne Boulevard Miami, FL 33131, US
Priority Data
09/224,89531.12.1998US
09/229,03912.01.1999US
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) LEUKOCYTE-DERIVED INTERFERON PREPARATIONS
(FR) PROCEDES ET COMPOSITION DE MELANGES NATURELS EXTREMEMENT PURIFIES D'INTERFERONS DE TYPE I DERIVES DES LEUCOCYTES
Abstract
(EN)
This invention relates to methods for isolating highly-purified mixtures of natural type I interferons from white blood cells. The invention also relates to highly-purified mixtures of natural type I interferons which resemble natural type interferon in that it includes 9 subtypes, i.e., alpha-1, alpha-2, alpha-5, alpha-7, alpha-8, alpha-10, alpha-14, alpha-21 and omega, giving rise to possibly 20 molecular species, including alpha-1a, alpha-1new, alpha-2a, alpha-2b, alpha-2c, alpha-5, alpha-5LG, alpha-7, alpha-8a, alpha-8c, alpha-10a, alpha-14a, alpha14-b, alpha 14-c, alpha-14LG, alpha-21a, alpha-21b, alpha-21c, omega and omega LG.
(FR)
Cette invention porte sur des procédés visant à isoler des leucocytes des mélanges extrêmement purifiés d'interférons naturels de type I. Cette invention porte également sur des mélanges extrêmement purifiés d'interférons naturels de type I qui ressemblent à l'interféron naturel comprenant 9 sous-types tels que alpha-1, alpha-2, alpha-5, alpha-7, alpha-8, alpha-10, alpha-14, alpha-21 et oméga, donnant éventuellement naissance à 20 espèces moléculaires telles que alpha-1a, alpha-1new, alpha-2a, alpha-2b, alpha-2c, alpha-5, alpha-5LG, alpha-7, alpha-8a, alpha-8c, alpha-10a, alpha-14a, alpha14-b, alpha 14-c, alpha-14LG, alpha-21a, alpha-21b, alpha-21c, oméga and oméga LG.
Also published as
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