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1. WO2000039125 - PIPERIDINES AS CCR5 MODULATORS

Publication Number WO/2000/039125
Publication Date 06.07.2000
International Application No. PCT/IB1999/001913
International Filing Date 01.12.1999
Chapter 2 Demand Filed 28.03.2000
IPC
C07D 401/04 2006.01
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
DHETEROCYCLIC COMPOUNDS
401Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
02containing two hetero rings
04directly linked by a ring-member-to-ring- member bond
C07D 401/14 2006.01
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
DHETEROCYCLIC COMPOUNDS
401Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
14containing three or more hetero rings
C07D 403/04 2006.01
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
DHETEROCYCLIC COMPOUNDS
403Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/167
02containing two hetero rings
04directly linked by a ring-member-to-ring- member bond
C07D 405/14 2006.01
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
DHETEROCYCLIC COMPOUNDS
405Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
14containing three or more hetero rings
C07D 413/04 2006.01
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
DHETEROCYCLIC COMPOUNDS
413Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
02containing two hetero rings
04directly linked by a ring-member-to-ring- member bond
C07D 413/14 2006.01
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
DHETEROCYCLIC COMPOUNDS
413Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
14containing three or more hetero rings
CPC
A61P 11/00
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
11Drugs for disorders of the respiratory system
A61P 11/06
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
11Drugs for disorders of the respiratory system
06Antiasthmatics
C07D 401/04
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
DHETEROCYCLIC COMPOUNDS
401Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
02containing two hetero rings
04directly linked by a ring-member-to-ring-member bond
C07D 401/14
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
DHETEROCYCLIC COMPOUNDS
401Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
14containing three or more hetero rings
C07D 403/04
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
DHETEROCYCLIC COMPOUNDS
403Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
02containing two hetero rings
04directly linked by a ring-member-to-ring-member bond
C07D 405/14
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
DHETEROCYCLIC COMPOUNDS
405Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
14containing three or more hetero rings
Applicants
  • PFIZER LIMITED [GB/GB]; Ramsgate Road Sandwich Kent CT13 9NJ, GB (GB)
  • PFIZER INC. [US/US]; 235 East 42nd Street New York, NY 10017, US (AE, AL, AM, AT, AU, AZ, BA, BB, BE, BF, BG, BJ, BR, BY, CA, CF, CG, CH, CI, CM, CN, CR, CU, CY, CZ, DE, DK, EE, ES, FI, FR, GA, GD, GE, GH, GM, GN, GR, GW, HR, HU, ID, IE, IL, IN, IS, IT, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MC, MD, MG, MK, ML, MN, MR, MW, MX, NE, NL, NO, NZ, PL, PT, RO, RU, SD, SE, SG, SI, SK, SL, SN, SZ, TD, TG, TJ, TM, TR, TT, TZ, UA, UG, UZ, VN, YU, ZA, ZW)
  • ARMOUR, Duncan, Robert [GB/GB]; GB (UsOnly)
  • PRICE, David, Anthony [GB/GB]; GB (UsOnly)
  • STAMMEN, Blanda, Luzia, Christa [GB/GB]; GB (UsOnly)
  • WOOD, Anthony [GB/GB]; GB (UsOnly)
  • PERROS, Manoussos [GB/GB]; GB (UsOnly)
  • EDWARDS, Martin, Paul [GB/GB]; GB (UsOnly)
Inventors
  • ARMOUR, Duncan, Robert; GB
  • PRICE, David, Anthony; GB
  • STAMMEN, Blanda, Luzia, Christa; GB
  • WOOD, Anthony; GB
  • PERROS, Manoussos; GB
  • EDWARDS, Martin, Paul; GB
Agents
  • SPIEGEL, Allen, J. @ c/o Simpson, Alison; Urquhart-Dykes & Lord 30 Welbeck Street London W1M 7PG, GB
Priority Data
9828420.123.12.1998GB
9922009.718.09.1999GB
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) PIPERIDINES AS CCR5 MODULATORS
(FR) PIPERIDINES UTILISES COMME MODULATEURS DE CCR5
Abstract
(EN)
Compounds of formula 1: [Region$g(a)] - [Region$g(b)] - [Region$g(g)] - [Region$g(d)] which are useful as modulators of chemokine activity. The invention also provides pharmaceutical formulations and methods of treatment using these compounds.
(FR)
L'invention concerne des composés de Formule 1: [Region$g(a)] - [Region$g(b)] - [Region$g(g)] - [Region$g(d)] utiles en tant que modulateurs de l'activité de la chimiokine. L'invention porte également sur des formules pharmaceutiques et sur des procédés de traitement, dans lesquels lesdits composés sont utilisés.
Also published as
CRCR2001-006393
CZPV2001-2297
GE5957/1
HRP20010478A
IS5941
NO20013149
NZ511796
SK200100876
SK8762001
TR2001/01867
TR2002/00938
UZ20010523
YUP-407/01
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