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1. WO2000038736 - MEDICINAL PREPARATIONS

Publication Number WO/2000/038736
Publication Date 06.07.2000
International Application No. PCT/JP1999/007278
International Filing Date 24.12.1999
Chapter 2 Demand Filed 19.07.2000
IPC
A61K 47/48 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
47Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
48the non-active ingredient being chemically bound to the active ingredient, e.g. polymer drug conjugates
CPC
A61K 47/54
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
47Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
50the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
51the non-active ingredient being a modifying agent
54the modifying agent being an organic compound
A61K 47/549
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
47Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
50the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
51the non-active ingredient being a modifying agent
54the modifying agent being an organic compound
549Sugars, nucleosides, nucleotides or nucleic acids
A61K 47/62
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
47Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
50the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
51the non-active ingredient being a modifying agent
62the modifying agent being a protein, peptide or polyamino acid
Applicants
  • KYOWA HAKKO KOGYO CO., LTD. [JP/JP]; 6-1, Othemachi 1-chome Chiyoda-ku Tokyo 100-8185, JP (AllExceptUS)
  • KATO, Yasuki [JP/JP]; JP (UsOnly)
  • KUSANO, Hiroko [JP/JP]; JP (UsOnly)
  • KAWAGUCHI, Yuji [JP/JP]; JP (UsOnly)
  • ITO, Kunio [JP/JP]; JP (UsOnly)
Inventors
  • KATO, Yasuki; JP
  • KUSANO, Hiroko; JP
  • KAWAGUCHI, Yuji; JP
  • ITO, Kunio; JP
Priority Data
PCT/JP98/0585724.12.1998JP
Publication Language Japanese (JA)
Filing Language Japanese (JA)
Designated States
Title
(EN) MEDICINAL PREPARATIONS
(FR) PREPARATIONS MEDICINALES
Abstract
(EN)
Medicinal preparations containing compounds obtained by reacting compounds having a free amino group with reducing saccharides. These preparations can improve the sustained effects of the compounds $i(in vivo) and release various compounds with a change in pH, which makes these preparations useful in exerting the effect of a specific compound at a target site.
(FR)
L'invention concerne des préparations médicinales contenant des composés obtenus en faisant réagir des composés contenant un groupe aminé libre avec des saccharides réducteurs. Ces préparations peuvent améliorer les effets prolongés des composés in vivo et libérer différents composés avec une modification de leur pH, ce qui rend ces préparations utiles pour la transmission de l'effet d'un composé spécifique sur un site cible.
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