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1. WO2000038735 - PHARMACEUTICAL PREPARATION

Publication Number WO/2000/038735
Publication Date 06.07.2000
International Application No. PCT/JP1998/005857
International Filing Date 24.12.1998
IPC
A61K 47/48 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
47Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
48the non-active ingredient being chemically bound to the active ingredient, e.g. polymer drug conjugates
CPC
A61K 47/54
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
47Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
50the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
51the non-active ingredient being a modifying agent
54the modifying agent being an organic compound
A61K 47/549
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
47Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
50the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
51the non-active ingredient being a modifying agent
54the modifying agent being an organic compound
549Sugars, nucleosides, nucleotides or nucleic acids
A61K 47/62
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
47Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
50the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
51the non-active ingredient being a modifying agent
62the modifying agent being a protein, peptide or polyamino acid
Applicants
  • KYOWA HAKKO KOGYO CO., LTD. [JP/JP]; 6-1, Ohtemachi 1-chome Chiyoda-ku Tokyo 100-8185, JP (AllExceptUS)
  • KATO, Yasuki [JP/JP]; JP (UsOnly)
  • KUSANO, Hiroko [JP/JP]; JP (UsOnly)
  • KAWAGUCHI, Yuji [JP/JP]; JP (UsOnly)
  • ITO, Kunio [JP/JP]; JP (UsOnly)
Inventors
  • KATO, Yasuki; JP
  • KUSANO, Hiroko; JP
  • KAWAGUCHI, Yuji; JP
  • ITO, Kunio; JP
Priority Data
Publication Language Japanese (JA)
Filing Language Japanese (JA)
Designated States
Title
(EN) PHARMACEUTICAL PREPARATION
(FR) PREPARATION PHARMACEUTIQUE
Abstract
(EN)
A pharmaceutical preparation containing a compound prepared by the reaction of a free amino compound with a reducing sugar. This preparation serves to improve the $i(in vivo) retentivity of the compound and dissociate various compounds in response to pH changes, thus being useful for treating the target site specifically with the compound.
(FR)
L'invention concerne une préparation pharmaceutique contenant un composé, obtenue par la mise en réaction d'un composé aminé libre avec un sucre réducteur. Cette réaction sert à améliorer la capacité de rétention $i(in vivo) du composé et à dissocier divers composés en réponse à des modifications de pH, ce qui permet de traiter le site cible spécifiquement à l'aide du composé.
Also published as
Latest bibliographic data on file with the International Bureau