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1. WO2000038728 - COMBINATIONS OF ILEAL BILE ACID TRANSPORT INHIBITORS AND BILE ACID SEQUESTRING AGENTS FOR CARDIOVASCULAR INDICATIONS

Publication Number WO/2000/038728
Publication Date 06.07.2000
International Application No. PCT/US1999/027949
International Filing Date 17.12.1999
Chapter 2 Demand Filed 21.07.2000
IPC
A61K 31/55 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
33Heterocyclic compounds
395having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
55having seven-membered rings, e.g. azelastine, pentylenetetrazole
A61K 31/575 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
56Compounds containing cyclopentahydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
575substituted in position 17 beta by a chain of three or more carbon atoms, e.g. cholane, cholestane, ergosterol, sitosterol
A61K 31/585 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
56Compounds containing cyclopentahydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
58containing heterocyclic rings, e.g. aldosterone, danazol, stanozolol, pancuronium, digitogenin
585containing lactone rings, e.g. oxandrolone, bufalin
A61K 31/785 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
74Synthetic polymeric materials
785Polymers containing nitrogen
A61K 45/06 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
45Medicinal preparations containing active ingredients not provided for in groups A61K31/-A61K41/132
06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
CPC
A61K 31/55
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
33Heterocyclic compounds
395having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
55having seven-membered rings, e.g. azelastine, pentylenetetrazole
A61K 31/575
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives, e.g. steroids
575substituted in position 17 beta by a chain of three or more carbon atoms, e.g. cholane, cholestane, ergosterol, sitosterol
A61K 31/585
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives, e.g. steroids
58containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
585containing lactone rings, e.g. oxandrolone, bufalin
A61K 31/785
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
74Synthetic polymeric materials
785Polymers containing nitrogen
A61K 45/06
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
45Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
Y10S 514/824
YSECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
10TECHNICAL SUBJECTS COVERED BY FORMER USPC
STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
514Drug, bio-affecting and body treating compositions
824Arteriosclerosis
Applicants
  • G.D. SEARLE LLC [US/US]; Corporate Patent Department P.O. Box 5110 Chicago, IL 60680-5110, US (AllExceptUS)
  • KELLER, Bradley, T. [US/US]; US (UsOnly)
  • GLENN, Kevin, C. [US/US]; US (UsOnly)
  • SCHUH, Joseph, R. [US/US]; US (UsOnly)
Inventors
  • KELLER, Bradley, T.; US
  • GLENN, Kevin, C.; US
  • SCHUH, Joseph, R.; US
Agents
  • ALTHERR, Robert, F. ; Banner & Witcoff, Ltd. 1001 G Street, N.W. Washingtgon, DC 20001-4597, US
  • WEISERT, Annekäte; Kraus & Weisert Thomas-Wimmer-Ring 15 D-80539 München, DE
Priority Data
60/113,95523.12.1998US
60/143,04307.07.1999US
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) COMBINATIONS OF ILEAL BILE ACID TRANSPORT INHIBITORS AND BILE ACID SEQUESTRING AGENTS FOR CARDIOVASCULAR INDICATIONS
(FR) COMBINAISONS D'INHIBITEURS DU TRANSPORT ILEAL DES ACIDES BILIAIRES ET D'AGENTS SEQUESTRANT LES ACIDES BILIAIRES UTILISEES DANS LE CADRE DE TROUBLES CARDIO-VASCULAIRES
Abstract
(EN)
The present invention provides combinations of cardiovascular therapeutic compounds for the prophylaxis or treatment of cardiovascular disease including hypercholesterolemia, atherosclerosis, or hyperlipidemia. Combinations disclosed include an ileal bile acid transport inhibitor combined with a bile acid sequestrant.
(FR)
La présente invention concerne des combinaisons de composés de thérapie cardio-vasculaire utilisées pour la prévention ou le traitement de troubles cardio-vasculaires telles que l'hypercholestérolémie, l'athérosclérose ou l'hyperlipémie. Cette invention fait intervenir des combinaisons comprenant un inhibiteur du transport iléal des acides biliaires combiné à un agent séquestrant des acides biliaires.
Also published as
CZPV2001-2345
ININ/PCT/2001/00543/DEL
NO20013159
NZ512535
ZA200105059
Latest bibliographic data on file with the International Bureau