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1. (WO2000038721) COMBINATIONS OF CHOLESTERYL ESTER TRANSFER PROTEIN INHIBITORS AND NICOTINIC ACID DERIVATIVES FOR CARDIOVASCULAR INDICATIONS
Latest bibliographic data on file with the International Bureau   

Pub. No.: WO/2000/038721 International Application No.: PCT/US1999/027942
Publication Date: 06.07.2000 International Filing Date: 17.12.1999
Chapter 2 Demand Filed: 21.07.2000
IPC:
A61K 31/55 (2006.01) ,A61K 31/575 (2006.01) ,A61K 31/585 (2006.01) ,A61K 31/785 (2006.01) ,A61K 45/06 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
33
Heterocyclic compounds
395
having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
55
having seven-membered rings, e.g. azelastine, pentylenetetrazole
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
56
Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
575
substituted in position 17 beta by a chain of three or more carbon atoms, e.g. cholane, cholestane, ergosterol, sitosterol
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
56
Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
58
containing heterocyclic rings, e.g. aldosterone, danazol, stanozolol, pancuronium, digitogenin
585
containing lactone rings, e.g. oxandrolone, bufalin
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
74
Synthetic polymeric materials
785
Polymers containing nitrogen
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
45
Medicinal preparations containing active ingredients not provided for in groups A61K31/-A61K41/132
06
Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
Applicants:
SIKORSKI, James, A. [US/US]; US (UsOnly)
GLENN, Kevin, C. [US/US]; US (UsOnly)
G.D. SEARLE LLC [US/US]; Corporate Patent Department P.O. Box 5110 Chicago, IL 60680-5110, US (AllExceptUS)
Inventors:
SIKORSKI, James, A.; US
GLENN, Kevin, C.; US
Agent:
ALTHERR, Robert, F. ; Banner & Witcoff, Ltd. 1001 G Street, N.W. Eleventh Floor Washington, DC 20001-4597, US
WEISERT, Annekäte; Kraus & Weisert Thomas-Wimmer-Ring 15 80539 Munich, DE
Priority Data:
60/113,95523.12.1998US
60/142,68407.07.1999US
Title (EN) COMBINATIONS OF CHOLESTERYL ESTER TRANSFER PROTEIN INHIBITORS AND NICOTINIC ACID DERIVATIVES FOR CARDIOVASCULAR INDICATIONS
(FR) COMBINAISONS D'INHIBITEURS DE LA PROTEINE DE TRANSFERT DU CHOLESTERYLE-ESTER ET DE DERIVES DE L'ACIDE NICOTINIQUE UTILISEES DANS LE CADRE DE TROUBLES CARDIO-VASCULAIRES
Abstract:
(EN) The present invention provides combinations of cardiovascular therapeutic compounds for the prophylaxis or treatment of cardiovascular disease including hypercholesterolemia, atherosclerosis, or hyperlipidemia. Combinations disclosed include a nicotinic acid derivative combined with a cholesteryl ester transfer protein (CETP) inhibitor.
(FR) La présente invention concerne des combinaisons de composés de thérapie cardio-vasculaire utilisées pour la prévention ou le traitement de troubles cardio-vasculaires telles que l'hypercholestérolémie, l'athérosclérose ou l'hyperlipémie. Cette invention fait intervenir des combinaisons comprenant un dérivé de l'acide nicotinique combiné avec un inhibiteur de la protéine de transfert du cholestéryle-ester (cholesteryl ester transfer protein / CETP).
Designated States: AE, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BY, CA, CH, CN, CR, CU, CZ, DE, DK, DM, EE, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, NO, NZ, PL, PT, RO, RU, SD, SE, SG, SI, SK, SL, TJ, TM, TR, TT, TZ, UA, UG, US, UZ, VN, YU, ZA, ZW
African Regional Intellectual Property Organization (ARIPO) (GH, GM, KE, LS, MW, SD, SL, SZ, TZ, UG, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (EPO) (AT, BE, CH, CY, DE, DK, ES, FI, FR, GB, GR, IE, IT, LU, MC, NL, PT, SE)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GW, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)