Processing

Please wait...

Settings

Settings

1. WO2000038713 - AGONISTS OR ANTAGONISTS OF CUTANEOUS T CELL-ATTRACTING CHEMOKINE (CTACK) OR VASOACTIVE INTESTINAL CONTRACTOR (VIC) CHEMOKINES

Publication Number WO/2000/038713
Publication Date 06.07.2000
International Application No. PCT/US1999/030819
International Filing Date 23.12.1999
Chapter 2 Demand Filed 16.06.2000
IPC
C07K 14/715 2006.01
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
14Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
435from animals; from humans
705Receptors; Cell surface antigens; Cell surface determinants
715for cytokines; for lymphokines; for interferons
C07K 16/24 2006.01
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
16Immunoglobulins, e.g. monoclonal or polyclonal antibodies
18against material from animals or humans
24against cytokines, lymphokines or interferons
C07K 16/28 2006.01
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
16Immunoglobulins, e.g. monoclonal or polyclonal antibodies
18against material from animals or humans
28against receptors, cell surface antigens or cell surface determinants
CPC
A61K 2039/505
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39Medicinal preparations containing antigens or antibodies
505comprising antibodies
A61P 17/00
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
17Drugs for dermatological disorders
A61P 17/02
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
17Drugs for dermatological disorders
02for treating wounds, ulcers, burns, scars, keloids, or the like
A61P 17/04
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
17Drugs for dermatological disorders
04Antipruritics
A61P 17/06
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
17Drugs for dermatological disorders
06Antipsoriatics
C07K 14/7158
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
14Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
435from animals; from humans
705Receptors; Cell surface antigens; Cell surface determinants
715for cytokines; for lymphokines; for interferons
7158for chemokines
Applicants
  • SCHERING CORPORATION [US/US]; 2000 Galloping Hill Road Kenilworth, NJ 07083-0530, US
Inventors
  • WANG, Wei; US
  • OLDHAM, Elizabeth, R.; US
  • SOTO, Hortensia; US
  • LUI, Ying; US
  • HUDAK, Susan, A.; US
  • HOMEY, Bernhard; US
  • MORALES, Janine, M.; US
  • KELLERMANN, Sirid-Aimee; US
  • MCEVOY, Leslie, M.; US
  • ZLOTNIK, Albert; US
Agents
  • MCLAUGHLIN, Jaye, P. ; Schering-Plough Corporation Patent Dept. K-6-1, 1990 2000 Galloping Hill Road Kenilworth, NJ 07033-0530, US
Priority Data
09/322,58027.05.1999US
60/113,85824.12.1998US
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) AGONISTS OR ANTAGONISTS OF CUTANEOUS T CELL-ATTRACTING CHEMOKINE (CTACK) OR VASOACTIVE INTESTINAL CONTRACTOR (VIC) CHEMOKINES
(FR) AGONISTES OU ANTAGONISTES DE LA CHEMOKINE D'ATTRACTION DES LYMPHOCYTES T (CTACK) OU DES CHEMOKINES DES CONTRACTEURS INTESTINAUX VASOACTIFS (VIC)
Abstract
(EN)
Agonists or antagonists of CTACK or Vic chemokines, and various methods of use in dermatological and related applications are provided. In particular, the method makes use of fact that the CTACK or Vic chemokines are specifically capable of inducing movement of a skin cell subset. Moreover, matching of ligand with GPR2 receptor in mammals provides methods of use.
(FR)
L'invention concerne des agonistes ou des antagonistes des chémokines CTACK ou Vic, ainsi que diverses méthodes d'utilisation dans des applications dermatologiques et apparentées. En particulier, la méthode utilise le fait que les chémokines CTACK ou Vic sont spécifiquement capables d'induire le mouvement d'un sous-ensemble de cellules de la peau. De plus, l'appariement du ligand au récepteur GPR2 chez des mammifères procure des méthodes d'utilisation.
Latest bibliographic data on file with the International Bureau