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1. WO2000036149 - ANTISENSE MODULATION OF AKT-1 EXPRESSION

Publication Number WO/2000/036149
Publication Date 22.06.2000
International Application No. PCT/US1999/013208
International Filing Date 10.06.1999
Chapter 2 Demand Filed 06.07.2000
IPC
C12N 15/11 2006.01
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
15Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
09Recombinant DNA-technology
11DNA or RNA fragments; Modified forms thereof
CPC
C12N 15/1137
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
15Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
09Recombinant DNA-technology
11DNA or RNA fragments; Modified forms thereof
113Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
1137against enzymes
Y02P 20/582
YSECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
20Technologies relating to chemical industry
50Improvements relating to the production of bulk chemicals
582Recycling of unreacted starting or intermediate materials
Applicants
  • ISIS PHARMACEUTICALS, INC. [US]/[US] (AllExceptUS)
  • MONIA, Brett, P. [US]/[US] (UsOnly)
  • COWSERT, Lex, M. [US]/[US] (UsOnly)
Inventors
  • MONIA, Brett, P.
  • COWSERT, Lex, M.
Agents
  • LICATA, Jane, Massey
Priority Data
09/212,77117.12.1998US
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) ANTISENSE MODULATION OF AKT-1 EXPRESSION
(FR) MODULATION ANTISENS DE L'EXPRESSION D'AKT-1
Abstract
(EN)
Antisense compounds, compositions and methods are provided for modulating the expression of Akt-1. The compositions comprise antisense compounds, particularly antisense oligonucleotides, targeted to nucleic acids encoding Akt-1. Methods of using these compounds for modulation of Akt-1 expression and for treatment of diseases associated with expression of Akt-1 are provided.
(FR)
L'invention concerne des procédés, des compositions et des composés antisens, pour la modulation de l'expression d'Atk-1. Lesdites compositions comprennent des composés antisens, notamment des oligonucléotides antisens, dirigés sur des acides nucléiques codant pour Akt-1. Des procédés d'utilisation desdits composés pour la modulation de l'expression d'Akt-1 et pour le traitement de maladies associées à l'expression d'Akt-1, sont également décrits.
Also published as
US09868278
Latest bibliographic data on file with the International Bureau