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1. WO2000036107 - COMPOSITIONS AND METHODS FOR THERAPY AND DIAGNOSIS OF OVARIAN CANCER

Publication Number WO/2000/036107
Publication Date 22.06.2000
International Application No. PCT/US1999/030270
International Filing Date 17.12.1999
Chapter 2 Demand Filed 10.07.2000
IPC
A61K 38/00 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
38Medicinal preparations containing peptides
A61K 39/00 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39Medicinal preparations containing antigens or antibodies
C07K 14/47 2006.1
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
14Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
435from animals; from humans
46from vertebrates
47from mammals
CPC
A61K 38/00
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
38Medicinal preparations containing peptides
A61K 39/00
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39Medicinal preparations containing antigens or antibodies
A61P 35/00
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
35Antineoplastic agents
A61P 37/04
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
37Drugs for immunological or allergic disorders
02Immunomodulators
04Immunostimulants
C07K 14/47
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
14Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
435from animals; from humans
46from vertebrates
47from mammals
C07K 14/70532
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
14Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
435from animals; from humans
705Receptors; Cell surface antigens; Cell surface determinants
70503Immunoglobulin superfamily
70532B7 molecules, e.g. CD80, CD86
Applicants
  • CORIXA CORPORATION [US]/[US]
Inventors
  • MITCHAM, Jennifer, L.
  • KING, Gordon, E.
  • ALGATE, Paul, A.
  • FRUDAKIS, Tony, N.
Agents
  • MAKI, David, J.
  • GOWSHALL, Jonathan V., Forrester & Boehmert
Priority Data
09/215,68117.12.1998US
09/216,00317.12.1998US
09/338,93323.06.1999US
09/404,87924.09.1999US
Publication Language English (en)
Filing Language English (EN)
Designated States
Title
(EN) COMPOSITIONS AND METHODS FOR THERAPY AND DIAGNOSIS OF OVARIAN CANCER
(FR) COMPOSITIONS ET PROCEDES DESTINES A LA THERAPIE ET AU DIAGNOSTIC DU CANCER DE L"OVAIRE
Abstract
(EN) Compositions and methods for the therapy and diagnosis of cancer, such as ovarian cancer, are disclosed. Compositions may comprise one or more ovarian carcinoma proteins, immunogenic portions thereof, polynucleotides that encode such portions or antibodies or immune system cells specific for such proteins. Such compositions may be used, for example, for the prevention and treatment of diseases such as ovarian cancer. Methods are further provided for identifying tumor antigens that are secreted from ovarian carcinomas and/or other tumors. Polypeptides and polynucleotides as provided herein may further be used for the diagnosis and monitoring of ovarian cancer.
(FR) L"invention concerne des compositions et des procédés destinés à la thérapie et au diagnostic de cancers tels que le cancer de l"ovaire. Les compositions peuvent comprendre une ou plusieurs protéines du carcinome de l"ovaire, leurs parties immunogéniques, des polynucléotides codant pour ces parties ou des anticorps ou des cellules du système immunitaire spécifique à ces protéines. Ces compositions peuvent s"utiliser, par exemple, dans la prévention et le traitement de maladies telles que le cancer de l"ovaire. L"invention concerne en outre des procédés pour identifier les antigènes tumoraux sécrétés depuis les carcinomes de l"ovaires et/ou d"autres tumeurs. En outre, les polypeptides et les polynucléotides fournis ici peuvent être utilisés dans le diagnostic et la surveillance du cancer de l"ovaire.
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