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1. WO2000035892 - PIPERAZINE ETHYLAMIDE DERIVATIVES WITH 5-HT1A RECEPTOR ACTIVITY

Publication Number WO/2000/035892
Publication Date 22.06.2000
International Application No. PCT/US1999/029953
International Filing Date 16.12.1999
Chapter 2 Demand Filed 07.07.2000
IPC
C07D 295/13 2006.01
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
DHETEROCYCLIC COMPOUNDS
295Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
04with substituted hydrocarbon radicals attached to ring nitrogen atoms
12substituted by singly or doubly bound nitrogen atoms
125with the ring nitrogen atoms and the substituent nitrogen atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
13to an acyclic saturated chain
CPC
A61P 15/10
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
15Drugs for genital or sexual disorders
10for impotence
A61P 25/00
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
25Drugs for disorders of the nervous system
A61P 25/20
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
25Drugs for disorders of the nervous system
20Hypnotics; Sedatives
A61P 25/22
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
25Drugs for disorders of the nervous system
22Anxiolytics
A61P 25/24
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
25Drugs for disorders of the nervous system
24Antidepressants
A61P 25/28
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
25Drugs for disorders of the nervous system
28for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
Applicants
  • AMERICAN HOME PRODUCTS CORPORATION [US]/[US]
Inventors
  • KELLY, Michael, Gerard
  • PALMER, Yvette, Latko
Agents
  • BARRETT, Rebecca, R.
  • WILEMAN, David, Francis
Priority Data
09/213,33617.12.1998US
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) PIPERAZINE ETHYLAMIDE DERIVATIVES WITH 5-HT1A RECEPTOR ACTIVITY
(FR) DERIVES DE PIPERAZINE ETHYLAMIDE A ACTIVITE DE RECEPTEUR 5-HT1A
Abstract
(EN)
Compounds of formula (I) are useful for the treatment of disorder of the central nervous system including anxiety, depression, panic, alcohol and drug addiction, sexual dysfunction, sleep disorders, migraine, obesity, cognitive disorders, and neurodegenerative diseases.
(FR)
La présente invention concerne des composés de formule (I) qui sont utiles dans le traitement de troubles du système nerveux central, y compris l'anxiété, la dépression, la panique, l'alcoolisme et la toxicomanie, les dysfonctionnements sexuels, les troubles du sommeil, la migraine, l'obésité, les troubles cognitifs, et les maladies neurodégénératives.
Also published as
CN99816165.9
NZ512266
Latest bibliographic data on file with the International Bureau