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1. WO2000035862 - AMIDO POLYBIGUANIDES AND THE USE THEREOF AS ANTIMICROBIAL AGENTS

Publication Number WO/2000/035862
Publication Date 22.06.2000
International Application No. PCT/US1999/030207
International Filing Date 17.12.1999
Chapter 2 Demand Filed 20.06.2000
IPC
A61L 12/14 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION, OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES
12Methods or apparatus for disinfecting or sterilising contact lenses; Accessories therefor
08using chemical substances
14Organic compounds not covered by groups A61L12/10 or A61L12/12100
C07C 279/28 2006.01
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
CACYCLIC OR CARBOCYCLIC COMPOUNDS
279Derivatives of guanidine, i.e. compounds containing the group the singly-bound nitrogen atoms not being part of nitro or nitroso groups
28having nitrogen atoms of guanidine groups bound to cyano groups, e.g. cyanoguanidines, dicyandiamides
C08G 73/00 2006.01
CCHEMISTRY; METALLURGY
08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
GMACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
73Macromolecular compounds obtained by reactions forming in the main chain of the macromolecule a linkage containing nitrogen, with or without oxygen or carbon, not provided for in groups C08G12/-C08G71/238
CPC
A61L 12/142
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION, OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES
12Methods or apparatus for disinfecting or sterilising contact lenses; Accessories therefor
08using chemical substances
14Organic compounds not covered by groups A61L12/10 or A61L12/12
141Biguanides, e.g. chlorhexidine
142Polymeric biguanides
A61P 27/04
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
27Drugs for disorders of the senses
02Ophthalmic agents
04Artificial tears; Irrigation solutions
A61P 27/16
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
27Drugs for disorders of the senses
16Otologicals
A61P 31/02
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
31Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
02Local antiseptics
C07C 279/28
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
CACYCLIC OR CARBOCYCLIC COMPOUNDS
279Derivatives of guanidine, i.e. compounds containing the group , the singly-bound nitrogen atoms not being part of nitro or nitroso groups
28having nitrogen atoms of guanidine groups bound to cyano groups, e.g. cyanoguanidines, dicyandiamides
C08G 73/00
CCHEMISTRY; METALLURGY
08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
GMACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
73Macromolecular compounds obtained by reactions forming a linkage containing nitrogen with or without oxygen or carbon in the main chain of the macromolecule, not provided for in groups C08G12/00 - C08G71/00
Applicants
  • ALCON LABORATORIES, INC. [US]/[US] (AllExceptUS)
  • PARK, Joonsup [US]/[US] (UsOnly)
  • McQUEEN, Nathaniel, D. [US]/[US] (UsOnly)
Inventors
  • PARK, Joonsup
  • McQUEEN, Nathaniel, D.
Agents
  • BROWN, Gregg, C.
Priority Data
60/112,97218.12.1998US
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) AMIDO POLYBIGUANIDES AND THE USE THEREOF AS ANTIMICROBIAL AGENTS
(FR) AMIDOPOLYBIGUANIDES ET UTILISATION DE CEUX-CI EN TANT QU'AGENTS ANTIMICROBIENS
Abstract
(EN)
Amido polybiguanides and their use as antimicrobial agents in pharmaceutical compositions are disclosed. A method of synthesis of amido polybiguanides is also disclosed. The amido polybiguanides are useful in the preservation of pharmaceutical compositions, particulary ophthalmic and otic pharmaceutical compositions and compositions for treating contact lenses. The compounds are especially useful for disinfecting contact lenses.
(FR)
L'invention concerne des amidopolybiguanides et l'utilisation de ceux-ci en tant qu'agents antimicrobiens dans des compositions pharmaceutiques. L'invention concerne également un procédé de synthèse d'amidopolybiguanides. Ces amidopolybiguanides sont utiles pour la conservation des compositions pharmaceutiques en particulier de compositions pharmaceutiques à usage ophtalmique et auriculaire ainsi que de compositions destinées au traitement des lentille de contact. Ces composés conviennent en particulier pour la désinfection des lentilles de contact.
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