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1. WO2000035295 - CONTROLLING RELEASE OF ACTIVE AGENTS FROM A CHEWING GUM COATING

Publication Number WO/2000/035295
Publication Date 22.06.2000
International Application No. PCT/US1999/029280
International Filing Date 10.12.1999
Chapter 2 Demand Filed 14.07.2000
IPC
A23G 4/00 2006.01
AHUMAN NECESSITIES
23FOODS OR FOODSTUFFS; THEIR TREATMENT, NOT COVERED BY OTHER CLASSES
GCOCOA; COCOA PRODUCTS, e.g. CHOCOLATE; SUBSTITUTES FOR COCOA OR COCOA PRODUCTS; CONFECTIONERY; CHEWING GUM; ICE-CREAM; PREPARATION THEREOF
4Chewing gum
A23G 4/02 2006.01
AHUMAN NECESSITIES
23FOODS OR FOODSTUFFS; THEIR TREATMENT, NOT COVERED BY OTHER CLASSES
GCOCOA; COCOA PRODUCTS, e.g. CHOCOLATE; SUBSTITUTES FOR COCOA OR COCOA PRODUCTS; CONFECTIONERY; CHEWING GUM; ICE-CREAM; PREPARATION THEREOF
4Chewing gum
02Apparatus specially adapted for manufacture or treatment of chewing gum
A61K 9/20 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9Medicinal preparations characterised by special physical form
20Pills, lozenges or tablets
A61K 9/24 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9Medicinal preparations characterised by special physical form
20Pills, lozenges or tablets
22Sustained or differential release type
24Layered or laminated unitary dosage forms
A61K 9/68 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9Medicinal preparations characterised by special physical form
68chewing gum type
CPC
A23G 4/025
AHUMAN NECESSITIES
23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
GCOCOA; COCOA PRODUCTS, e.g. CHOCOLATE; SUBSTITUTES FOR COCOA OR COCOA PRODUCTS; CONFECTIONERY; CHEWING GUM; ICE-CREAM; PREPARATION THEREOF
4Chewing gum
02Apparatus specially adapted for manufacture or treatment of chewing gum
025for coating or surface-finishing
A23G 4/06
AHUMAN NECESSITIES
23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
GCOCOA; COCOA PRODUCTS, e.g. CHOCOLATE; SUBSTITUTES FOR COCOA OR COCOA PRODUCTS; CONFECTIONERY; CHEWING GUM; ICE-CREAM; PREPARATION THEREOF
4Chewing gum
06characterised by the composition ; containing organic or inorganic compounds
A23G 4/064
AHUMAN NECESSITIES
23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
GCOCOA; COCOA PRODUCTS, e.g. CHOCOLATE; SUBSTITUTES FOR COCOA OR COCOA PRODUCTS; CONFECTIONERY; CHEWING GUM; ICE-CREAM; PREPARATION THEREOF
4Chewing gum
06characterised by the composition ; containing organic or inorganic compounds
064containing inorganic compounds
A23G 4/068
AHUMAN NECESSITIES
23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
GCOCOA; COCOA PRODUCTS, e.g. CHOCOLATE; SUBSTITUTES FOR COCOA OR COCOA PRODUCTS; CONFECTIONERY; CHEWING GUM; ICE-CREAM; PREPARATION THEREOF
4Chewing gum
06characterised by the composition ; containing organic or inorganic compounds
068containing plants or parts thereof, e.g. fruits, seeds, extracts
A23G 4/10
AHUMAN NECESSITIES
23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
GCOCOA; COCOA PRODUCTS, e.g. CHOCOLATE; SUBSTITUTES FOR COCOA OR COCOA PRODUCTS; CONFECTIONERY; CHEWING GUM; ICE-CREAM; PREPARATION THEREOF
4Chewing gum
06characterised by the composition ; containing organic or inorganic compounds
10characterised by the carbohydrates used, e.g. polysaccharides
A23G 4/126
AHUMAN NECESSITIES
23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
GCOCOA; COCOA PRODUCTS, e.g. CHOCOLATE; SUBSTITUTES FOR COCOA OR COCOA PRODUCTS; CONFECTIONERY; CHEWING GUM; ICE-CREAM; PREPARATION THEREOF
4Chewing gum
06characterised by the composition ; containing organic or inorganic compounds
12containing microorganisms or enzymes; containing paramedical or dietetical agents, e.g. vitamins
126containing vitamins, antibiotics
Applicants
  • WM. WRIGLEY JR. COMPANY [US]/[US]
Inventors
  • SONG, Joo, H.
  • TOWNSEND, Donald, J.
  • RECORD, David, W.
  • TYRPIN, Henry, T.
  • RUSSEL, Michael, P.
  • SCHNELL, Philip, G.
Priority Data
06/112,38915.12.1998US
09/389,21102.09.1999US
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) CONTROLLING RELEASE OF ACTIVE AGENTS FROM A CHEWING GUM COATING
(FR) LIBERATION PROLONGEE DE PRINCIPES ACTIFS D'UN ENROBAGE DE GOMME A MACHER
Abstract
(EN)
A method for producing a coated chewing gum with a controlled release of an active agent, as well as the chewing gum so produced, is obtained by physically modifying an active agent's properties by coating and drying. An active agent is coated by encapsulation, partially coated by agglomeration, entrapped by absorption, or treated by multiple steps of encapsulation, agglomeration, and absorption. The coated active agent is then co-dried and particle sized to produce a release-modified active agent. When incorporated into a chewing gum coating, these particles release into the mouth but mask bitter and other off-tastes in the mouth, and are readily ingested.
(FR)
L'invention concerne un procédé permettant de produire une gomme à mâcher enrobée renfermant un principe actif à libération prolongée. Cette invention concerne également la gomme à mâcher ainsi produite, que l'on obtient en modifiant physiquement les propriétés dudit principe actif en soumettant celui-ci à un enrobage et à un séchage. Selon ce procédé, un principe actif est enrobé par encapsulation, partiellement enrobé par agglomération, piégé par absorption, ou traité par une succession d'étapes d'encapsulation, d'agglomération, et d'absorption. Ce principe actif enrobé est ensuite séché en compagnie d'autres ingrédients puis ramené à une taille particulaire, de manière à produire un principe actif à libération modifiée. Enfin, une fois incorporées dans un enrobage de gomme à mâcher, les particules se diffusent dans la bouche pour masquer l'amertume ou tout autre goût désagréable, tout en étant rapidement ingérées.
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