Some content of this application is unavailable at the moment.
If this situation persist, please contact us atFeedback&Contact
1. (WO2000032601) PROCESS FOR PREPARING CROSS-BRIDGED TETRAAZA MACROCYCLES
Latest bibliographic data on file with the International Bureau

Pub. No.: WO/2000/032601 International Application No.: PCT/US1999/027316
Publication Date: 08.06.2000 International Filing Date: 18.11.1999
Chapter 2 Demand Filed: 18.05.2000
IPC:
B01J 31/18 (2006.01) ,C07D 487/08 (2006.01) ,C07F 13/00 (2006.01)
B PERFORMING OPERATIONS; TRANSPORTING
01
PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
J
CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS, COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
31
Catalysts comprising hydrides, coordination complexes or organic compounds
16
containing coordination complexes
18
containing nitrogen, phosphorus, arsenic or antimony
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
D
HETEROCYCLIC COMPOUNDS
487
Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/-C07D477/183
02
in which the condensed system contains two hetero rings
08
Bridged systems
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
F
ACYCLIC, CARBOCYCLIC, OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
13
Compounds containing elements of the 7th Group of the Periodic System
Applicants:
THE PROCTER & GAMBLE COMPANY [US/US]; One Procter & Gamble Plaza Cincinnati, OH 45202, US (AllExceptUS)
HILER, George, Douglas, II [US/US]; US (UsOnly)
PERKINS, Christopher, Mark [US/US]; US (UsOnly)
Inventors:
HILER, George, Douglas, II; US
PERKINS, Christopher, Mark; US
Agent:
REED, T., David ; The Procter & Gamble Company 5299 Spring Grove Avenue Cincinnati, OH 45217-1087, US
Priority Data:
60/110,30930.11.1998US
Title (EN) PROCESS FOR PREPARING CROSS-BRIDGED TETRAAZA MACROCYCLES
(FR) PROCEDE DE PREPARATION DE TETRAAZA MACROCYCLES PONTES TRANSVERSALEMENT
Abstract:
(EN) The present invention relates to a process for preparing a cross-bridged tetraaza macrocyclic ligand having formula (I) wherein each R is independently C1-C8 linear or branched alkyl, -(CH2)xCO2M, and mixtures thereof; provided both of the R units are not methyl; M is hydrogen or a salt forming cation; x is from 1 to 6; each index n is independently from 0 to 3; by contacting a di-quaternary $i(cis) tetracycle precursor with hydrogen in the presence of a palladium catalyst in an aqueous solution having a pH of at least about 10 at a temperature of about 40 °C to about 100 °C.
(FR) La présente invention concerne un procédé de préparation d'un ligand tétraaza macrocyclique de formule (I) dans laquelle chaque R est, de manière indépendante, un alkyle linéaire C1-C8 ou un alkyle ramifié (CH2)xCO2M, et des mélanges de ce ligand, pourvu que les deux R ne soient pas des groupes méthyle, M est un hydrogène ou un cation formant un sel, x prend les valeurs de 1 à 6, chaque indice n prend, de manière indépendante, les valeurs de 1 à 3. Ce procédé consiste à mettre en contact un précurseur tétracyclique $i(cis) di-quaternaire avec de l'hydrogène en présence d'un catalyseur au palladium dans une solution aqueuse de pH au moins égal à environ 10 et à une température comprise entre environ 40 °C et environ 100°C.
Designated States: AE, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BY, CA, CH, CN, CR, CU, CZ, DE, DK, DM, EE, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, NO, NZ, PL, PT, RO, RU, SD, SE, SG, SI, SK, SL, TJ, TM, TR, TT, UA, UG, US, UZ, VN, YU, ZA, ZW
African Regional Intellectual Property Organization (ARIPO) (GH, GM, KE, LS, MW, SD, SL, SZ, TZ, UG, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, CH, CY, DE, DK, ES, FI, FR, GB, GR, IE, IT, LU, MC, NL, PT, SE)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GW, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)