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1. WO2000029626 - RHADINO VIRUS LANA ACTS IN TRANS ON A UNIT OF RHADINO VIRUS DNA TO MEDIATE EFFICIENT EPISOME PERSISTENCE

Publication Number WO/2000/029626
Publication Date 25.05.2000
International Application No. PCT/US1999/027508
International Filing Date 19.11.1999
Chapter 2 Demand Filed 16.06.2000
IPC
C07K 14/03 2006.01
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
14Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
005from viruses
01DNA viruses
03Herpetoviridae, e.g. pseudorabies virus
C12Q 1/70 2006.01
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
1Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
70involving virus or bacteriophage
CPC
C07K 14/005
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
14Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
005from viruses
C12N 2710/16422
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
2710dsDNA Viruses
00011dsDNA Viruses
16011Herpesviridae
16411Rhadinovirus, e.g. human herpesvirus 8
16422New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
C12Q 1/706
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS
1Measuring or testing processes involving enzymes, nucleic acids or microorganisms
70involving virus or bacteriophage
701Specific hybridization probes
706for hepatitis
Y10S 435/975
YSECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
10TECHNICAL SUBJECTS COVERED BY FORMER USPC
STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
435Chemistry: molecular biology and microbiology
975Kit
Applicants
  • KIEFF, Elliott, D. [US]/[US]
  • BALLESTAS, Mary, E. [US]/[US]
  • KAYE, Kenneth, M. [US]/[US]
Inventors
  • KIEFF, Elliott, D.
  • BALLESTAS, Mary, E.
  • KAYE, Kenneth, M.
Agents
  • PASTERNAK, Thomas, G.
Priority Data
09/298,56821.04.1999US
60/109,42219.11.1998US
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) RHADINO VIRUS LANA ACTS IN TRANS ON A UNIT OF RHADINO VIRUS DNA TO MEDIATE EFFICIENT EPISOME PERSISTENCE
(FR) ACTION EN TRANS DE LA LANA DU RHADINOVIRUS SUR UNE UNITE D'ADN DE RHADINOVIRUS PERMETTANT D'INDUIRE UNE PERSISTANCE EFFICACE DES EPISOMES
Abstract
(EN)
The LANA is necessary for the efficient persistence of Rhadino Virus DNA in mammalian cells. Methods and assays to determine the interest compounds that modulate LANA are disclosed.
(FR)
La protéine LANA est nécessaire à la persistance efficace de l'ADN de rhadinovirus dans des cellules de mammifères. L'invention concerne des méthodes et des tests permettant de déterminer les composés d'intérêt qui modulent LANA.
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