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1. (WO2000029441) NOVEL G PROTEIN-COUPLED RECEPTOR PROTEIN, ITS DNA AND LIGAND THEREOF
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2000/029441    International Application No.:    PCT/JP1999/006283
Publication Date: 25.05.2000 International Filing Date: 11.11.1999
Chapter 2 Demand Filed:    06.01.2000    
IPC:
C07K 14/72 (2006.01), G01N 33/566 (2006.01)
Applicants: TAKEDA CHEMICAL INDUSTRIES, LTD. [JP/JP]; 1-1, Doshomashi 4-chome Chuo-ku Osaka-shi Osaka 541-0045 (JP) (For All Designated States Except US).
WATANABE, Takuya [JP/JP]; (JP) (For US Only).
KIKUCHI, Kuniko [JP/JP]; (JP) (For US Only).
TERAO, Yasuko [JP/JP]; (JP) (For US Only).
SHINTANI, Yasushi [JP/JP]; (JP) (For US Only).
HINUMA, Shuji [JP/JP]; (JP) (For US Only).
FUKUSUMI, Shoji [JP/JP]; (JP) (For US Only).
FUJII, Ryo [JP/JP]; (JP) (For US Only).
HOSOYA, Masaki [JP/JP]; (JP) (For US Only).
KITADA, Chieko [JP/JP]; (JP) (For US Only)
Inventors: WATANABE, Takuya; (JP).
KIKUCHI, Kuniko; (JP).
TERAO, Yasuko; (JP).
SHINTANI, Yasushi; (JP).
HINUMA, Shuji; (JP).
FUKUSUMI, Shoji; (JP).
FUJII, Ryo; (JP).
HOSOYA, Masaki; (JP).
KITADA, Chieko; (JP)
Agent: TAKAHASHI, Shuichi; Osaka Plant of Takeda Chemical Industries, Ltd. 17-85, Jusohonmachi 2-chome Yodogawa-ku Osaka-shi Osaka 532-0024 (JP)
Priority Data:
10/323759 13.11.1998 JP
11/60030 08.03.1999 JP
11/106812 14.04.1999 JP
11/166672 14.06.1999 JP
11/221640 04.08.1999 JP
11/259818 14.09.1999 JP
Title (EN) NOVEL G PROTEIN-COUPLED RECEPTOR PROTEIN, ITS DNA AND LIGAND THEREOF
(FR) NOUVELLE PROTEINE RECEPTRICE COUPLEE A LA PROTEINE G, SON ADN ET SON LIGAND
Abstract: front page image
(EN)A novel polypeptide, its peptide fragments or salts thereof; a process for producing this polypeptide; a receptor of the polypeptide; drugs containing the polypeptide, etc.; an antibody against the polypeptide; a method/kit for screening compounds promoting or inhibiting the activity of the polypeptide; the compounds obtained by the screening; and drugs, etc. containing these compounds. The above polypeptide or its peptide fragments are usable as, for example, remedies for nervous diseases and somatostatin excretion promoters. The above antibody is usable in, for example, quantitating the polypeptide in a liquid specimen. Further, the polypeptide is useful as a reagent for screening the compounds promoting or inhibiting the activity of the polypeptide.
(FR)L'invention concerne un nouveau polypeptide et ses fragments ou sels, un procédé de production dudit polypeptide, un récepteur dudit polypeptide, des médicaments contenant ledit polypeptide, etc., un anticorps anti-polypeptide. L'invention concerne également une méthode et une trousse pour cribler des composés pouvant promouvoir ou inhiber l'activité du polypeptide, les composés obtenus par ce criblage, et des médicaments, etc., contenant ces composés. Le polypeptide ci-décrit ou ses fragments peptidiques s'utilisent, par exemple, comme remèdes contre les maladies nerveuses ou comme promoteurs de la sécrétion de la somatostatine. L'anticorps ci-décrit s'utilise, par exemple, pour quantifier le polypeptide dans un échantillon liquide. Le polypeptide de l'invention est en outre utile comme réactif intervenant dans le criblage des composés pouvant promouvoir ou inhiber l'activité du polypeptide.
Designated States: AE, AL, AM, AU, AZ, BA, BB, BG, BR, BY, CA, CN, CR, CU, CZ, DM, EE, GD, GE, HR, HU, ID, IL, IN, IS, JP, KG, KR, KZ, LC, LK, LR, LT, LV, MA, MD, MG, MK, MN, MX, NO, NZ, PL, RO, RU, SG, SI, SK, SL, TJ, TM, TR, TT, TZ, UA, US, UZ, VN, YU, ZA.
African Regional Intellectual Property Organization (GH, GM, KE, LS, MW, SD, SL, SZ, TZ, UG, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, CH, CY, DE, DK, ES, FI, FR, GB, GR, IE, IT, LU, MC, NL, PT, SE)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GW, ML, MR, NE, SN, TD, TG).
Publication Language: Japanese (JA)
Filing Language: Japanese (JA)