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Machine translation
1. (WO2000029029) COMPOSITIONS AND METHODS FOR PRODUCING VASCULAR OCCLUSION
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2000/029029    International Application No.:    PCT/IB1999/001809
Publication Date: 25.05.2000 International Filing Date: 10.11.1999
Chapter 2 Demand Filed:    09.06.2000    
IPC:
A61K 47/48 (2006.01), C07K 16/28 (2006.01)
Applicants: NOVOLYTICS INC. [CA/CA]; Aberhart Centre, 2nd floor, West Wing, 11402 University Avenue, Edmonton, Alberta T6G 2J3 (CA) (For All Designated States Except US).
STEWART, Michael, William [CA/CA]; (CA) (For US Only).
PERSON, Roland, Henryk [CA/CA]; (CA) (For US Only).
NOUJAIM, Antoine [CA/CA]; (CA) (For US Only)
Inventors: STEWART, Michael, William; (CA).
PERSON, Roland, Henryk; (CA).
NOUJAIM, Antoine; (CA)
Priority Data:
60/108,129 12.11.1998 US
Title (EN) COMPOSITIONS AND METHODS FOR PRODUCING VASCULAR OCCLUSION
(FR) COMPOSITIONS ET METHODES GENERATRICES D'OCCLUSIONS VASCULAIRES
Abstract: front page image
(EN)The present invention relates generally to methods and compositions for targeting, delivering, and activating platelet-dependent vascular occlusion agents. In particular, antibodies carrying platelet binding agents are targeted to hyperplastic cells or tissues, such as the vasculature of solid tumor masses; the platelet binding agent then binds and activates platelets, which in turn bind and activate other platelets. This process results in the formation of a platelet-mediated thrombus-causing vessel occlusion.
(FR)L'invention porte sur d'une manière générale sur des méthodes et composition assurant le ciblage, la délivrance et l'activation d'agents d'occlusions vasculaire liés aux plaquettes. En particulier les anticorps porteurs d'agents liant les plaquettes sont dirigés vers des cellules ou des tissus hyperplastiques tels que des masses tumorales solides. Lesdits agents fixent et activent certaines plaquettes qui à leur tour en fixent et activent d'autres. Ce processus aboutit à la formation d'un thrombus induit par les plaquettes, qui provoque l'occlusion des vaisseaux.
Designated States: AE, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BY, CA, CH, CN, CU, CZ, DE, DK, EE, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MD, MG, MK, MN, MW, MX, NO, NZ, PL, PT, RO, RU, SD, SE, SG, SI, SK, SL, TJ, TM, TR, TT, UA, UG, US, UZ, VN, YU, ZA, ZW.
African Regional Intellectual Property Organization (GH, GM, KE, LS, MW, SD, SL, SZ, TZ, UG, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, CH, CY, DE, DK, ES, FI, FR, GB, GR, IE, IT, LU, MC, NL, PT, SE)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)