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Machine translation
1. (WO2000028983) NOVEL 4-DEDIMETHY LAMINOTETRA CYCLINE DERIVATIVES
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2000/028983    International Application No.:    PCT/US1999/027304
Publication Date: 25.05.2000 International Filing Date: 18.11.1999
Chapter 2 Demand Filed:    19.05.2000    
IPC:
C07C 235/82 (2006.01), C07C 237/26 (2006.01), C07C 245/20 (2006.01), C07C 247/18 (2006.01), C07C 329/20 (2006.01), C07D 295/13 (2006.01)
Applicants: COLLAGENEX PHARMACEUTICALS, INC. [US/US]; 41 University Drive Newtown, PA 18940 (US) (For All Designated States Except US).
ASHLEY, Robert, A. [US/US]; (US) (For US Only).
HLAVKA, Joseph, J. [US/US]; (US) (For US Only)
Inventors: ASHLEY, Robert, A.; (US).
HLAVKA, Joseph, J.; (US)
Agent: BARON, Ronald, J.; Hoffmann & Baron, LLP 6900 Jericho Turnpike Syosset, NY 11791 (US)
Priority Data:
09/195,013 18.11.1998 US
60/108,948 18.11.1998 US
Title (EN) NOVEL 4-DEDIMETHY LAMINOTETRA CYCLINE DERIVATIVES
(FR) NOUVEAUX DERIVES DE 4-DEDIMETHY LAMINOTETRA CYCLINE
Abstract: front page image
(EN)The present invention provides new chemically modified 4-dedimethylaminotetracycline compounds that can be substituted at the 7,8, and/or 9 positions and methods for preparing the 4-dedimethylamino tetracycline compounds. Other tetracycline compounds are the 4-dedimethylaminotetracycline derivatives with an oxime group, NH-Alkyl, or N-NH-Alkyl group at the C4 position. The present invention also provides a method of treating a mammal suffering from conditions or diseases by administering to the mammal an effective amount of the new chemically modified 4-dedimethylamino tetracycline compounds.
(FR)L'invention concerne de nouveaux composés chimiquement modifiés de 4-dédiméthylaminotétracycline pouvant être substitués au niveau des positions 7,8 et/ou 9, ainsi que des procédés servant à préparer ces composés de 4-dédiméthylaminotétracycline. D'autres composés de tétracycline sont les dérivés de 4-dédiméthylaminotétracycline comportant un groupe oxime, NH-Alkyle ou N-NH-Alkyle en position C4. Elle concerne également un procédé servant à traiter un mammifère atteint de troubles ou de maladies par administration à ce mammifère d'une quantité efficace de ces nouveaux composés chimiquement modifiés de 4-dédiméthylaminotétracycline.
Designated States: AE, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BY, CA, CH, CN, CR, CU, CZ, DE, DK, DM, EE, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, NO, NZ, PL, PT, RO, RU, SD, SE, SG, SI, SK, SL, TJ, TM, TR, TT, TZ, UA, UG, US, UZ, VN, YU, ZA, ZW.
African Regional Intellectual Property Organization (GH, GM, KE, LS, MW, SD, SL, SZ, TZ, UG, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, CH, CY, DE, DK, ES, FI, FR, GB, GR, IE, IT, LU, MC, NL, PT, SE)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)