WIPO logo
Mobile | Deutsch | Español | Français | 日本語 | 한국어 | Português | Русский | 中文 | العربية |
PATENTSCOPE

Search International and National Patent Collections
World Intellectual Property Organization
Search
 
Browse
 
Translate
 
Options
 
News
 
Login
 
Help
 
Machine translation
1. (WO2000028969) METHODS FOR PREPARING COATED DRUG PARTICLES AND PHARMACEUTICAL FORMULATIONS THEREOF
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2000/028969    International Application No.:    PCT/US1999/027401
Publication Date: 25.05.2000 International Filing Date: 18.11.1999
Chapter 2 Demand Filed:    16.06.2000    
IPC:
A61K 9/00 (2006.01), A61K 9/50 (2006.01), A61K 9/51 (2006.01), C23C 14/22 (2006.01), C23C 14/28 (2006.01)
Applicants: UNIVERSITY OF FLORIDA [US/US]; P.O. Box 115500 Gainesville, FL 32611-5500 (US) (For All Designated States Except US).
TALTON, James, D. [US/US]; (US) (For US Only).
HOCHHAUS, Guenther [US/US]; (US) (For US Only).
SINGH, Rajiv, K. [US/US]; (US) (For US Only).
FITZ-GERALD, James, M. [US/US]; (US) (For US Only)
Inventors: TALTON, James, D.; (US).
HOCHHAUS, Guenther; (US).
SINGH, Rajiv, K.; (US).
FITZ-GERALD, James, M.; (US)
Agent: MOORE, Mark, D.; Williams, Morgan & Amerson, P.C. 7676 Hillmont Suite 250 Houston, TX 77040 (US).
GLAWE, DELFS, MOLL & PARTNER; Rothenbaumchaussee 58 D-20148 Hamburg (DE)
Priority Data:
60/108,847 18.11.1998 US
60/110,291 30.11.1998 US
Title (EN) METHODS FOR PREPARING COATED DRUG PARTICLES AND PHARMACEUTICAL FORMULATIONS THEREOF
(FR) PROCEDES DE PREPARATION DE PARTICULES DE MEDICAMENT ENROBEES ET FORMULATIONS PHARMACEUTIQUES CORRESPONDANTES
Abstract: front page image
(EN)Disclosed are methods using pulsed laser ablation to prepare coated drug particles of uniform size and thickness. The coated drug particles ranged in size from several nanometers to several millimeters in diameter size, and were coated with organic polymer particle having average diameter sizes from about 1 to 50 nm. In illustrative embodiments, coated drug particles or drug delivery particles are disclosed comprising a biodegradable or biocompatible polymer coating having controlled thickness and controlled coating uniformity, that offer superior pharmaceutical properties for controlled delivery and increased bioavailability.
(FR)La présente invention concerne des procédés de préparation de particules de médicaments enrobées, de taille et d'épaisseur uniforme, qui font appel à la technique de l'ablation par laser pulsé. Ces particules présentent un diamètre allant de plusieurs nanomètres à plusieurs millimètres et sont enrobées d'un polymère organique d'un diamètre moyen compris entre 1 et 50 nm environ. Selon des modes de réalisation type, les particules de médicament enrobées ou les particules d'administration de médicaments comprennent un revêtement polymère biodégradable ou biocompatible d'une épaisseur et d'une uniformité précises qui possèdent des propriétés pharmaceutiques supérieures en termes d'administration maîtrisée et de biodisponibilité accrue.
Designated States: AE, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BY, CA, CH, CN, CR, CU, CZ, DE, DK, DM, EE, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MD, MG, MK, MN, MW, MX, NO, NZ, PL, PT, RO, RU, SD, SE, SG, SI, SK, SL, TJ, TM, TR, TT, TZ, UA, UG, US, UZ, VN, YU, ZA, ZW.
African Regional Intellectual Property Organization (GH, GM, KE, LS, MW, SD, SL, SZ, TZ, UG, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, CH, CY, DE, DK, ES, FI, FR, GB, GR, IE, IT, LU, MC, NL, PT, SE)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)