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Machine translation
1. (WO2000028944) USE OF SUCCINIC ACID OR SALTS THEREOF AND METHOD OF TREATING INSULIN RESISTANCE
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2000/028944    International Application No.:    PCT/RU1998/000374
Publication Date: 25.05.2000 International Filing Date: 12.11.1998
IPC:
A61K 31/194 (2006.01)
Applicants: POMYTKIN, Igor Anatolievich [RU/RU]; (RU).
KOLESOVA, Olga Evgenievna [RU/RU]; (RU).
UKHANOVA, Tatiyana Jurievna [RU/RU]; (RU) (For All Designated States Except US).
VERTELETSKY, Pavel Vasilievich [RU/RU]; (RU)
Inventors: POMYTKIN, Igor Anatolievich; (RU).
KOLESOVA, Olga Evgenievna; (RU).
UKHANOVA, Tatiyana Jurievna; (RU)
Agent: ERMAKOVA, Elena Anatolievna; ul. 1-ya Novokuzminskaya, 10-2-100 Moscow, 109377 (RU)
Priority Data:
Title (EN) USE OF SUCCINIC ACID OR SALTS THEREOF AND METHOD OF TREATING INSULIN RESISTANCE
(FR) UTILISATION D'ACIDE SUCCINIQUE OU DE SELS DE CELUI-CI, ET PROCEDE DE TRAITEMENT DE L'INSULINO-RESISTANCE
Abstract: front page image
(EN)The invention relates to the use of succinic acid or pharmaceutically acceptable salts thereof for manufacture of medicaments or nutritional supplements effective for treating of insulin resistance in mammals, preferably in non-insulin dependent diabetic humans. Insulin resistance is associated with disorders such as Non-insulin dependent Diabetes Mellitus (NIDDM) and its chronic complications, gestational diabetes mellitus, impaired glucose tolerance, obesity, aging, atherosclerosis, syndrome X, cardiovascular disease, AIDS, cancer, wasting/cachecxia, sepsis, trauma associated with burns, malnutrition, lupus and other autoimmune diseases, endocrine diseases, hyperuricemia, hyperlipidemia, dyslipidemia, polycystic ovary syndrome or complications arising from athletic activity. The invention provides a method of treating insulin resistance in mammals, preferably in humans, which comprises administering to a mammal in need thereof succinic acid or a pharmaceutically acceptable salts thereof.
(FR)L'invention concerne l'utilisation d'acide succinique ou de sels de celui-ci, acceptables sur le plan pharmacologique, dans la fabrication de médicaments ou de compléments nutritionnels efficaces dans le traitement de l'insulino-résistance chez les mammifères, de préférence chez des humains diabétiques non insulino-dépendants. L'insulino-résistance est associée à des troubles tels que le diabète sucré non insulino-dépendant et les complications chroniques de celui-ci, le diabète sucré de la grossesse, la tolérance insuffisante au glucose, l'obésité, la vieillesse, l'athérosclérose, le syndrome X, les maladies cardio-vasculaires, le SIDA, le cancer, l'atrophie/cachexie, la septicémie, les lésions associées aux brûlures, la malnutrition, le lupus et autres maladies auto-immunes, les maladies endocriniennes, l'hyperuricémie, l'hyperlipidémie, la dyslipidémie, la polykystose ovarienne, ou des complications provenant d'une activité sportive. L'invention concerne un procédé de traitement de l'insulino-résistance chez les mammifères, notamment chez l'homme, consistant à administrer à un mammifère nécessitant un tel traitement, de l'acide succinique ou des sels de celui-ci, acceptables sur le plan pharmacologique.
Designated States: AL, AM, AT, AU, AZ, BA, BB, BG, BR, BY, CA, CH, CN, CU, CZ, DE, DK, EE, ES, FI, GB, GE, GH, GM, HU, ID, IL, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MD, MG, MK, MN, MW, MX, NO, NZ, PL, PT, RO, RU, SD, SE, SG, SI, SK, SL, TJ, TM, TR, TT, UA, UG, US, UZ, VN, YU, ZW.
African Regional Intellectual Property Organization (GH, GM, KE, LS, MW, SD, SZ, UG, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, CH, CY, DE, DK, ES, FI, FR, GB, GR, IE, IT, LU, MC, NL, PT, SE)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)