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Machine translation
1. (WO2000028075) $i(BACILLUS) STRAIN AND ASSAY METHODS
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2000/028075    International Application No.:    PCT/GB1999/003738
Publication Date: 18.05.2000 International Filing Date: 10.11.1999
Chapter 2 Demand Filed:    26.05.2000    
IPC:
C07K 14/32 (2006.01), C12N 15/75 (2006.01), C12Q 1/18 (2006.01), C12Q 1/68 (2006.01)
Applicants: ISIS INNOVATION LIMITED [GB/GB]; Ewert House Ewert Place Summertown Oxford OX2 7BZ (GB) (For All Designated States Except US).
ERRINGTON, Jeffrey [GB/GB]; (GB) (For US Only)
Inventors: ERRINGTON, Jeffrey; (GB)
Agent: ROQUES, Sarah, E.; J.A. KEMP & Co. 14 South Square, Gray's Inn London WC1R 5LX (GB)
Priority Data:
9824682.0 10.11.1998 GB
Title (EN) $i(BACILLUS) STRAIN AND ASSAY METHODS
(FR) SOUCHE DE BACILLUS ET TECHNIQUE D'ANALYSE
Abstract: front page image
(EN)Micro-organisms having a chromosome in which at least one gene has been partly or wholly replaced by a homologous gene from another micro-organism, and an artificially introduced reporter gene is present and is expressed in a manner related to a homologous gene expression product. Panels of such micro-organisms are also described. Methods of assessing an agent for antibiotic activity and using the agent as an antibiotic. Methods of killing or inhibiting the growth of bacteria.
(FR)L'invention concerne des micro-organismes possédant un chromosome dans lequel au moins un gène a été partiellement ou totalement remplacé par un gène homologue provenant d'un autre micro-organisme et qui comporte un gène rapporteur introduit artificiellement, dont l'expression est proche d'un produit d'expression dudit gène homologue; des panels desdits micro-organismes; des techniques permettant de déterminer l'activité antibiotique d'un agent et d'utiliser ledit agent comme antibiotique; ainsi que des techniques permettant de tuer les bactéries ou d'inhiber leur croissance.
Designated States: JP, US.
European Patent Office (AT, BE, CH, CY, DE, DK, ES, FI, FR, GB, GR, IE, IT, LU, MC, NL, PT, SE).
Publication Language: English (EN)
Filing Language: English (EN)