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Machine translation
1. (WO2000027802) BICYCLIC SIGNAL TRANSDUCTION INHIBITORS, COMPOSITIONS CONTAINING THEM & USES THEREOF
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2000/027802    International Application No.:    PCT/US1999/026986
Publication Date: 18.05.2000 International Filing Date: 12.11.1999
Chapter 2 Demand Filed:    08.06.2000    
IPC:
C07C 237/48 (2006.01), C07D 313/08 (2006.01), C07F 9/12 (2006.01), C07F 9/38 (2006.01), C07F 9/40 (2006.01), C07F 9/655 (2006.01)
Applicants: ARIAD PHARMACEUTICALS, INC. [US/US]; 26 Landsdowne Street Cambridge, MA 02139-4234 (US) (For All Designated States Except US).
SHAKESPEARE, William, C. [US/US]; (US) (For US Only).
YANG, Michael, G. [US/US]; (US) (For US Only).
SUNDARAMOORTHI, Rajeswari [US/US]; (US) (For US Only).
BOHACEK, Regine [US/US]; (US) (For US Only).
EYERMANN, Charles, Joseph [US/US]; (US) (For US Only).
SAWYER, Tomi, K. [US/US]; (US) (For US Only)
Inventors: SHAKESPEARE, William, C.; (US).
YANG, Michael, G.; (US).
SUNDARAMOORTHI, Rajeswari; (US).
BOHACEK, Regine; (US).
EYERMANN, Charles, Joseph; (US).
SAWYER, Tomi, K.; (US)
Agent: BERSTEIN, David, L.; Ariad Pharmaceuticals, Inc. 26 Landsdowne Street Cambridge, MA 02139-4234 (US)
Priority Data:
60/108,106 12.11.1998 US
Title (EN) BICYCLIC SIGNAL TRANSDUCTION INHIBITORS, COMPOSITIONS CONTAINING THEM & USES THEREOF
(FR) INHIBITEURS DE TRANSDUCTION DE SIGNAUX BICYCLIQUES, COMPOSITIONS LES CONTENANT ET UTILISATION DE CES DERNIERES
Abstract: front page image
(EN)This invention concerns compounds for inhibiting intracellular signal transduction, especially intracellular signal transduction mediated by one or more molecular interactions involving a phosphotyrosine-containing protein. This invention also relates to pharmaceutical compositions containing the compounds and prophylactic and therapeutic methods involving pharmaceutical and veterinary administration of the compounds. The compounds are of the formula (I) as defined herein.
(FR)L'invention concerne des composés permettant l'inhibition de la transduction de signaux intracellulaires, en particulier par l'intermédiaire d'une ou de plusieurs interactions moléculaires faisant intervenir une protéine contenant de la phosphotyrosine. L'invention concerne également des compositions pharmaceutiques contenant lesdits composés, ainsi que des méthodes prophylactiques et thérapeutiques reposant sur l'administration pharmaceutique et vétérinaire desdits composés. Ces composés présentent la structure de la formule (I), telle que définie dans le descriptif.
Designated States: CA, JP, US.
European Patent Office (AT, BE, CH, CY, DE, DK, ES, FI, FR, GB, GR, IE, IT, LU, MC, NL, PT, SE).
Publication Language: English (EN)
Filing Language: English (EN)