WIPO logo
Mobile | Deutsch | Español | Français | 日本語 | 한국어 | Português | Русский | 中文 | العربية |
PATENTSCOPE

Search International and National Patent Collections
World Intellectual Property Organization
Search
 
Browse
 
Translate
 
Options
 
News
 
Login
 
Help
 
Machine translation
1. (WO2000027417) PHARMACEUTICAL COMPOSITIONS COMPRISING SYNTHETIC PEPTIDE COPOLYMERS AND METHODS FOR PREVENTING AND TREATING GVHD AND HVGD
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2000/027417    International Application No.:    PCT/US1999/027107
Publication Date: 18.05.2000 International Filing Date: 12.11.1999
Chapter 2 Demand Filed:    09.06.2000    
IPC:
A61K 38/00 (2006.01), A61K 38/16 (2006.01), A61L 27/22 (2006.01)
Applicants: YEDA RESEARCH AND DEVELOPMENT CO. LTD. [IL/IL]; Weizmann Institute Of Science P.O. Box 95 76100 Rehovot (IL) (For All Designated States Except US).
AHARONI, Rina [IL/IL]; (IL) (For US Only).
TEITELBAUM, Dvora [IL/IL]; (IL) (For US Only).
ARNON, Ruth [IL/IL]; (IL) (For US Only).
SELA, Michael [IL/IL]; (IL) (For US Only).
MCINNIS, Patricia, A. [US/US]; (US) (SD only)
Inventors: AHARONI, Rina; (IL).
TEITELBAUM, Dvora; (IL).
ARNON, Ruth; (IL).
SELA, Michael; (IL)
Agent: BROWDY AND NEIMARK, P.L.L.C.; 624 Ninth Street, N.W. Suite 300 Washington, DC 20001-5303 (US).
LATKER, Norman, J.; Browdy and Neimark, P.L.L.C. Suite 300 624 Ninth Street N.W. Washington, DC 20001 (US)
Priority Data:
60/108,184 12.11.1998 US
60/145,219 23.07.1999 US
Title (EN) PHARMACEUTICAL COMPOSITIONS COMPRISING SYNTHETIC PEPTIDE COPOLYMERS AND METHODS FOR PREVENTING AND TREATING GVHD AND HVGD
(FR) COMPOSITIONS PHARMACEUTIQUES COMPRENANT DES COPOLYMERES DE PEPTIDES SYNTHETIQUES ET METHODES DE PREVENTION ET DE TRAITEMENT DE LA REACTION DU GREFFON CONTRE L'HOTE (GVHD) ET DE LA REACTION DE L'HOTE CONTRE LE GREFFON (HVGD)
Abstract: front page image
(EN)Compositions and methods for treating and preventing host-versus-graft disease and graft-versus-host disease comprising as active ingredient random copolymers of amino acids comprising one amino acid from at least three of the following groups: (a) lysine and arginine; (b) glutamic acid and aspartic acid; (c) alanine and glycine; and (d) tyrosine and tryptophan; with the proviso that the random copolymer is not Copolymer 1 or D-Copolymer 1 when the disease being treated is graft-versus-host disease.
(FR)L'invention concerne des compositions et des méthodes de traitement et de prévention de la réaction du greffon contre l'hôte et de la réaction de l'hôte contre le greffon, qui comprennent comme matière active des copolymères aléatoires d'acides aminés dont l'un est sélectionné dans au moins trois des groupes suivants : (a) lysine et arginine ; (b) acide glutamique et acide aspartique ; (c) alanine et glycin ; et (d) tyrosine et tryptophan ; à condition que le copolymère aléatoire ne soit pas le copolymère 1 ou le copolymère D 1 lorsque la maladie à traiter est la réaction de l'hôte contre le greffon.
Designated States: AE, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BY, CA, CH, CN, CR, CU, CZ, DE, DK, DM, EE, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MD, MG, MK, MN, MW, MX, NO, NZ, PL, PT, RO, RU, SD, SE, SG, SI, SK, SL, TJ, TM, TR, TT, TZ, UA, UG, US, UZ, VN, YU, ZA, ZW.
African Regional Intellectual Property Organization (GH, GM, KE, LS, MW, SD, SL, SZ, TZ, UG, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, CH, CY, DE, DK, ES, FI, FR, GB, GR, IE, IT, LU, MC, NL, PT, SE)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)