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1. (WO2000026676) CANCER-ASSOCIATED ANTIGENS AND METHODS OF THEIR IDENTIFICATION
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2000/026676    International Application No.:    PCT/US1999/025936
Publication Date: 11.05.2000 International Filing Date: 03.11.1999
Chapter 2 Demand Filed:    31.05.2000    
IPC:
G01N 33/574 (2006.01), G01N 33/68 (2006.01)
Applicants: CELL GENESYS, INC. [US/US]; 342 Lakeside Drive Foster City, CA 94404 (US)
Inventors: ANDO, Dale; (US).
CHANG, Ju-Fay; (US).
MCARTHUR, James; (US).
ROBERTS, Margo; (US).
SIMONS, Jonathon; (US)
Agent: NAKAMURA, Dean, H.; Roylance, Abrams, Berdo & Goodman, L.L.P. 1300 19th Street, N.W., Suite 600 Washington, DC 20036 (US)
Priority Data:
60/106,795 03.11.1998 US
Title (EN) CANCER-ASSOCIATED ANTIGENS AND METHODS OF THEIR IDENTIFICATION
(FR) ANTIGENES ASSOCIES AU CANCER ET PROCEDES D'IDENTIFICATION CORRESPONDANTS
Abstract: front page image
(EN)The present invention provides novel, isolated, tumor-associated antigens, and methods for identifying such antigens in a biological sample, and of screening for the presence of such an antigen in a biological specimen, wherein the tumor antigen identified reacts with serum from a subject treated with a vaccine comprising a cytokine and proliferation-incompetent tumor cells which express the tumor-associated antigen. Also provided are kits for carrying out the methods of the invention.
(FR)La présente invention concerne de nouveaux antigènes isolés associés au cancer et des procédés pour identifier ces antigènes dans un échantillon biologique ainsi que des procédés de criblage permettant d'identifier la présence des antigènes de ce type dans un spécimen biologique. L'antigène tumoral identifié réagit avec le sérum pris chez un sujet traité avec un vaccin comprenant un cytokine et des cellules tumorales incapables de prolifération qui expriment l'antigène associé à la tumeur. L'invention concerne aussi des kits permettant de mettre en oeuvre les procédés de l'invention.
Designated States: AL, AM, AT, AU, AZ, BA, BB, BG, BR, BY, CA, CH, CN, CU, CZ, DE, DK, EE, ES, FI, GB, GE, GH, HU, IL, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MD, MG, MK, MN, MW, MX, NO, NZ, PL, PT, RO, RU, SD, SE, SG, SI, SK, SL, TJ, TM, TR, TT, UA, UG, UZ, VN, YU, ZW.
African Regional Intellectual Property Organization (GH, GM, KE, LS, MW, SD, SL, SZ, TZ, UG, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, CH, CY, DE, DK, ES, FI, FR, GB, GR, IE, IT, LU, MC, NL, PT, SE)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)