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Machine translation
1. (WO2000026634) COMPOSITIONS AND METHODS FOR SCREENING AGENTS THAT INHIBIT MAPK MEDIATED ANTI-APOPTOTIC SIGNALS
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2000/026634    International Application No.:    PCT/US1999/025514
Publication Date: 11.05.2000 International Filing Date: 29.10.1999
Chapter 2 Demand Filed:    26.05.2000    
IPC:
C07K 14/435 (2006.01)
Applicants: MASSACHUSETTS INSTITUTE OF TECHNOLOGY [US/US]; 77 Massachusetts Avenue Cambridge, MA 02139-4307 (US)
Inventors: STELLER, Hermann; (US).
AGAPITE, Julie; (US).
BERGMANN, Andreas; (US).
MCCALL, Kimberly; (US)
Agent: CARROLL, Peter, G.; Medlen & Carroll, LLP Suite 2200 220 Montgomery Street San Francisco, CA 94104 (US)
Priority Data:
60/106,108 29.10.1998 US
09/431,573 29.10.1999 US
Title (EN) COMPOSITIONS AND METHODS FOR SCREENING AGENTS THAT INHIBIT MAPK MEDIATED ANTI-APOPTOTIC SIGNALS
(FR) COMPOSITIONS ET PROCEDES PERMETTANT L'IDENTIFICATION D'AGENTS INHIBANT LES SIGNAUX ANTI-APOPTOTIQUES TRANSMIS PAR MAPK
Abstract: front page image
(EN)Nucleic acid sequences and corresponding translated products of novel mutant forms of the $i(Drosophila hid) gene are described. Such sequences and products are useful in screening methods for identifying and testing antagonists of Hid phosphorylation, in particular, compositions modifying MAPK phosphorylation of Hid.
(FR)L'invention concerne des séquences d'acide nucléique de nouvelles formes mutantes du gène $i(Drosophila hid), ainsi que les produits traduits correspondants. On utilise ces séquences et ces produits dans des méthodes de criblage afin d'identifier et de tester des antagonistes de la phosphorylation de Hid, en particulier des compositions qui modifient la phosphorylation de Hid par MAPK.
Designated States: CA, JP.
European Patent Office (AT, BE, CH, CY, DE, DK, ES, FI, FR, GB, GR, IE, IT, LU, MC, NL, PT, SE).
Publication Language: English (EN)
Filing Language: English (EN)