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Machine translation
1. (WO2000026357) TRANSGENIC AND CLONED MAMMALS
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2000/026357    International Application No.:    PCT/US1999/025710
Publication Date: 11.05.2000 International Filing Date: 02.11.1999
Chapter 2 Demand Filed:    02.06.2000    
IPC:
A61K 38/00 (2006.01), C07K 14/81 (2006.01), C12N 15/85 (2006.01), C12N 15/87 (2006.01)
Applicants: GENZYME TRANSGENIC CORP. [US/US]; 175 Crossing Boulevard Framingham, MA 01701 (US) (For All Designated States Except US).
ECHELARD, Yann [US/US]; (US) (For US Only).
BEHBODI, Esmail [US/US]; (US) (For US Only).
ZIOMEK, Carol [US/US]; (US) (For US Only).
GAVIN, William [US/US]; (US) (For US Only).
MELICAN, David [US/US]; (US) (For US Only)
Inventors: ECHELARD, Yann; (US).
BEHBODI, Esmail; (US).
ZIOMEK, Carol; (US).
GAVIN, William; (US).
MELICAN, David; (US)
Agent: MYERS, Louis; Fish & Richardson P.C. 225 Franklin Street Boston, MA 02110-2804 (US)
Priority Data:
60/106,728 02.11.1998 US
09/298,508 22.04.1999 US
09/298,971 23.04.1999 US
60/131,328 26.04.1999 US
Title (EN) TRANSGENIC AND CLONED MAMMALS
(FR) MAMMIFERES TRANSGENIQUES ET CLONES
Abstract: front page image
(EN)The invention features methods of making cloned and transgenic mammals, e.g., goats. The methods include making a somatic cell line, e.g., a transgenic somatic cell line which can be used as a donor cell, methods of producing a cloned or transgenic mammal by introducing the genome of a somatic cell into an enucleated oocyte, preferably a naturally matured oocyte which is telophase, to form a reconstructed embryo, and methods of transferring the reconstructed embryo. The invention also includes cell lines, reconstructed embryos and cloned or transgenic mammals.
(FR)L'invention présente des procédés permettant de produire des mammifères (p.ex. chèvres) clonés ou transgéniques. Parmi les procédés figurent la réalisation d'une lignée cellulaire somatique, p.ex. une lignée cellulaire somatique transgénique pouvant être utilisée comme cellule donneuse; des procédés de production d'un mammifère cloné ou transgénique par l'introduction du génome d'une cellule somatique dans un ovocyte énucléé, de préférence ayant atteint maturation de manière naturelle en au stade de télophase, afin de former un embryon reconstitué; ainsi que des procédés de transfert de l'embryon reconstitué. L'invention concerne aussi des lignées cellulaires, des embryons reconstitués et des mammifères clonés ou transgéniques.
Designated States: AE, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BY, CA, CH, CN, CR, CU, CZ, DE, DK, DM, EE, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MD, MG, MK, MN, MW, MX, NO, NZ, PL, PT, RO, RU, SD, SE, SG, SI, SK, SL, TJ, TM, TR, TT, UA, UG, US, UZ, VN, YU, ZA, ZW.
African Regional Intellectual Property Organization (GH, GM, KE, LS, MW, SD, SL, SZ, TZ, UG, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, CH, CY, DE, DK, ES, FI, FR, GB, GR, IE, IT, LU, MC, NL, PT, SE)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)