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Machine translation
1. (WO2000026342) METHOD OF INTERFERING WITH CELL PROLIFERATION
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2000/026342    International Application No.:    PCT/US1999/025359
Publication Date: 11.05.2000 International Filing Date: 29.10.1999
Chapter 2 Demand Filed:    05.05.2000    
IPC:
A61K 38/17 (2006.01), A61K 38/39 (2006.01), C07K 16/18 (2006.01), C07K 16/28 (2006.01)
Applicants: NORTHWESTERN UNIVERSITY [US/US]; 1801 Maple Avenue Evanston, IL 60201-3135 (US)
Inventors: JONES, Jonathan, C., R.; (US).
BAKER, Scott, E.; (US)
Agent: CROOK, Wannell, M.; Sheridan Ross P.C. Suite 1200 1560 Broadway Denver, CO 80202-5141 (US)
Priority Data:
60/106,491 30.10.1998 US
Title (EN) METHOD OF INTERFERING WITH CELL PROLIFERATION
(FR) METHODE PERMETTANT D'INFLUENCER LA PROLIFERATION CELLULAIRE
Abstract: front page image
(EN)The invention provides a method for interfering with cell proliferation by contacting cells with a molecule which binds to, and inhibits the function of, laminin 5 or $g(a)¿3?$g(b)¿1? integrins. This method is useful for inhibiting the proliferation of a variety of cell types, particularly tumor cells. Also provided are pharmaceutical compositions comprising a molecule of the invention and a pharmaceutically-acceptable carrier.
(FR)L'invention se rapporte à une méthode permettant d'influencer la prolifération cellulaire et consistant à mettre en contact une molécule qui se lie à la laminine 5 ou aux intégrines $g(a)¿3?$g(b)¿1? et qu'elle inhibe. Cette méthode permet d'inhiber la prolifération de nombreux types de cellules, notamment les cellules tumorales. L'invention se rapporte également à des compositions pharmaceutiques comportant une molécule telle que celle décrite ci-dessus et un excipient pharmaceutiquement acceptable.
Designated States: AU, CA, JP.
European Patent Office (AT, BE, CH, CY, DE, DK, ES, FI, FR, GB, GR, IE, IT, LU, MC, NL, PT, SE).
Publication Language: English (EN)
Filing Language: English (EN)