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1. (WO2000026224) NOVEL MACROLIDE ANTIBIOTICS
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2000/026224    International Application No.:    PCT/IB1999/001701
Publication Date: 11.05.2000 International Filing Date: 18.10.1999
Chapter 2 Demand Filed:    06.03.2000    
IPC:
C07H 17/08 (2006.01)
Applicants: PFIZER PRODUCTS INC. [US/US]; Eastern Point Road, Groton, CT 06340 (US) (For All Designated States Except US).
KANEKO, Takushi [JP/US]; (US) (For US Only)
Inventors: KANEKO, Takushi; (US)
Agent: SPIEGEL, Allen, J.; c/o Simpson, Alison, Urquhart-Dykes & Lord, 30 Welbeck Street, London W1M 7PG (GB)
Priority Data:
60/106,836 03.11.1998 US
Title (EN) NOVEL MACROLIDE ANTIBIOTICS
(FR) NOUVEAUX ANTIBIOTIQUES MACROLIDE
Abstract: front page image
(EN)This invention relates to compounds of formula (I) wherein a, R?1¿, R?2¿, R?3¿, R?4¿, R?5¿, R?6¿ and X are each as defined above, and to pharmaceutically acceptable salts thereof, useful as potent antibacterial and antiprotozoal agents that may be used to treat various bacterial and protozoal infections and disorders related to such infections. The invention also relates to pharmaceutical compositions containing the compounds of formula (I) and to methods of treating bacterial and protozoal infections by administering the compounds of formula (I).
(FR)Composés de formule (I) dans laquelle a, R?1¿, R?2¿, R?3¿, R?4¿, R?5¿, R?6¿ et X sont tels que définis dans le descriptif, ainsi que sels desdits composés acceptables sur le plan pharmaceutique, qui sont utiles en tant qu'agents antibactériens et antiprotozoaires puissants pouvant être utilisés pour traiter diverses infections bactériennes et protozooses, ainsi que des états pathologiques liés à ces infections. La présente invention concerne également des compositions pharmaceutiques contenant les composés de formule (I) et les procédés de traitement d'infections bactériennes et de protozooses par l'administration desdits composés de formule (I).
Designated States: AE, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BY, CA, CH, CN, CR, CU, CZ, DE, DK, EE, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MD, MG, MK, MN, MW, MX, NO, NZ, PL, PT, RO, RU, SD, SE, SG, SI, SK, SL, TJ, TM, TR, TT, UA, UG, US, UZ, VN, YU, ZA, ZW.
African Regional Intellectual Property Organization (GH, GM, KE, LS, MW, SD, SL, SZ, TZ, UG, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, CH, CY, DE, DK, ES, FI, FR, GB, GR, IE, IT, LU, MC, NL, PT, SE)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)