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1. (WO2000026223) METHODS AND COMPOSITIONS FOR THE MANUFACTURE OF HIGHLY POTENT ANTHRACYCLINE-BASED ANTITUMOR AGENTS
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2000/026223    International Application No.:    PCT/US1999/025672
Publication Date: 11.05.2000 International Filing Date: 02.11.1999
Chapter 2 Demand Filed:    30.05.2000    
IPC:
C07H 15/252 (2006.01)
Applicants: BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM [US/US]; 221 West 7th Street Austin, TX 78701 (US) (For All Designated States Except US).
PRIEBE, Waldemar [PL/US]; (US) (For US Only).
PRZEWLOKA, Teresa [PL/US]; (US) (For US Only).
FOKT, Izabela [PL/US]; (US) (For US Only).
LING, Yi-He [CN/US]; (US) (For US Only).
PEREZ-SOLER, Roman [US/US]; (US) (For US Only)
Inventors: PRIEBE, Waldemar; (US).
PRZEWLOKA, Teresa; (US).
FOKT, Izabela; (US).
LING, Yi-He; (US).
PEREZ-SOLER, Roman; (US)
Agent: WILSON, Mark, B.; Arnold White & Durkee 750 Bering Drive Houston, TX 77057-2198 (US).
CASALONGA, Axel; Bureau D.A. Casalonga-Josse Morassistrasse 8 D-80469 Munich (DE)
Priority Data:
60/106.730 02.11.1998 US
Title (EN) METHODS AND COMPOSITIONS FOR THE MANUFACTURE OF HIGHLY POTENT ANTHRACYCLINE-BASED ANTITUMOR AGENTS
(FR) METHODES ET COMPOSITIONS DE PRODUCTION D"AGENTS ANTITUMORAUX TRES PUISSANTS A BASE D"ANTHRACYCLINE
Abstract: front page image
(EN)The present invention discloses new and novel substituted anthracyclines having a three ring system or other DNA binding moities. These congeners show high activity $i(in vitro) against several tumor cell lines. The invention also describes anthracycline-based DNA alkylators.
(FR)La présente invention concerne de nouvelles anthracyclines à substitution présentant un système à trois cycles ou d"autres fractions de liaison d"ADN. Ces congénères présentent une activité élevée $i(in vitro) contre plusieurs lignées cellulaires tumorales. L"invention concerne également des agents alcoylants d"ADN à base d"anthracycline.
Designated States: AE, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BY, CA, CH, CN, CR, CU, CZ, DE, DK, DM, EE, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, NO, NZ, PL, PT, RO, RU, SD, SE, SG, SI, SK, SL, TJ, TM, TR, TT, TZ, UA, UG, US, UZ, VN, YU, ZA, ZW.
African Regional Intellectual Property Organization (GH, GM, KE, LS, MW, SD, SL, SZ, TZ, UG, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, CH, CY, DE, DK, ES, FI, FR, GB, GR, IE, IT, LU, MC, NL, PT, SE)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)