WIPO logo
Mobile | Deutsch | Español | Français | 日本語 | 한국어 | Português | Русский | 中文 | العربية |
PATENTSCOPE

Search International and National Patent Collections
World Intellectual Property Organization
Search
 
Browse
 
Translate
 
Options
 
News
 
Login
 
Help
 
Machine translation
1. (WO2000026195) NOVEL AMINO ACID HETEROCYCLIC AMIDE DERIVATIVES USEFUL AS NITRIC OXIDE SYNTHASE INHIBITORS
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2000/026195    International Application No.:    PCT/US1999/021468
Publication Date: 11.05.2000 International Filing Date: 20.10.1999
Chapter 2 Demand Filed:    22.05.2000    
IPC:
C07D 213/75 (2006.01), C07D 233/88 (2006.01), C07D 249/04 (2006.01), C07D 257/06 (2006.01), C07D 277/46 (2006.01), C07D 307/33 (2006.01), C07D 403/04 (2006.01), C07D 403/12 (2006.01), C07D 407/12 (2006.01), C07D 409/12 (2006.01), C07D 453/02 (2006.01), C07F 9/6524 (2006.01)
Applicants: G.D. SEARLE & CO. [US/US]; Corporate Patent Department P.O. Box 5110 Chicago, IL 60680-5110 (US) (For All Designated States Except US).
HANSEN, Donald, W., Jr. [US/US]; (US) (For US Only).
HAGEN, Timothy, J. [US/US]; (US) (For US Only).
HALLINAN, E., Ann [US/US]; (US) (For US Only).
PITZELE, Barnett, S. [US/US]; (US) (For US Only).
WEBBER, R., Keith [US/US]; (US) (For US Only).
RUEPPEL, Melvin, L. [US/US]; (US) (For US Only)
Inventors: HANSEN, Donald, W., Jr.; (US).
HAGEN, Timothy, J.; (US).
HALLINAN, E., Ann; (US).
PITZELE, Barnett, S.; (US).
WEBBER, R., Keith; (US).
RUEPPEL, Melvin, L.; (US)
Agent: SCRIVNER, Alan, S.; G.D. Searle & Co. Corporate Patent Dept. P.O. Box 5110 Chicago, IL 60680-5110 (US).
WEISERT, Annekäte; Kraus, Weisert & Partner Thomas-Wimmer-Ring 15 D-80539 München 22 (DE)
Priority Data:
60/106,514 30.10.1998 US
Title (EN) NOVEL AMINO ACID HETEROCYCLIC AMIDE DERIVATIVES USEFUL AS NITRIC OXIDE SYNTHASE INHIBITORS
(FR) NOUVEAUX DERIVES AMIDE HETEROCYCLIQUES D'AMINOACIDES UTILISES COMME INHIBITEURS DE L'OXYDE NITRIQUE SYNTHASE
Abstract: front page image
(EN)Amino acid heterocyclic amide derivatives useful as nitric oxide synthase inhibitors, having formula (I) and pharmaceutically acceptable salts and prodrugs, wherein: J is O or S; B is NR?5¿R?11¿ wherein R?11¿ is selected from a heterocyclic ring in which at least one member of the ring is carbon and in which 1 to about 4 heteroatoms are independently selected from oxygen, nitrogen and sulfur and said heterocyclic ring may be optionally substituted.
(FR)L'invention concerne des dérivés amide hérérocycliques d'aminoacides utilisés comme inhibiteurs de l'oxyde nitrique synthase, ainsi que les sels et promédicaments pharmaceutiquement acceptables de ces dérivés. Ces dérivés sont représentés par la formule (I), dans laquelle J représente O ou S; B représente NR?5¿R?11¿, où R?11¿ est sélectionné à partir d'un noyau hétérocyclique dans lequel un élément au moins du noyau est un carbone et dans lequel 1 à environ 4 hétéroatomes sont indépendamment choisis parmi l'oxygène, l'azote et le soufre, ledit noyau hétérocyclique pouvant être éventuellement substitué.
Designated States: AE, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BY, CA, CH, CN, CR, CU, CZ, DE, DK, DM, EE, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MD, MG, MK, MN, MW, MX, NO, NZ, PL, PT, RO, RU, SD, SE, SG, SI, SK, SL, TJ, TM, TR, TT, TZ, UA, UG, US, UZ, VN, YU, ZA, ZW.
African Regional Intellectual Property Organization (GH, GM, KE, LS, MW, SD, SL, SZ, TZ, UG, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, CH, CY, DE, DK, ES, FI, FR, GB, GR, IE, IT, LU, MC, NL, PT, SE)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)