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1. WO2000025838 - ELEMENT PROVIDED WITH A FIBRIN LAYER, PREPARATION AND USE THEREOF

Publication Number WO/2000/025838
Publication Date 11.05.2000
International Application No. PCT/US1999/025955
International Filing Date 04.11.1999
Chapter 2 Demand Filed 02.06.2000
IPC
A61L 27/34 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION, OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES
27Materials for prostheses or for coating prostheses
28Materials for coating prostheses
34Macromolecular materials
A61L 27/50 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION, OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES
27Materials for prostheses or for coating prostheses
50Materials characterised by their function or physical properties
A61L 27/60 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION, OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES
27Materials for prostheses or for coating prostheses
50Materials characterised by their function or physical properties
60Materials for use in artificial skin
B01D 69/10 2006.01
BPERFORMING OPERATIONS; TRANSPORTING
01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
DSEPARATION
69Semi-permeable membranes for separation processes or apparatus characterised by their form, structure or properties; Manufacturing processes specially adapted therefor
10Supported membranes; Membrane supports
B01D 71/74 2006.01
BPERFORMING OPERATIONS; TRANSPORTING
01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
DSEPARATION
71Semi-permeable membranes for separation processes or apparatus characterised by the material; Manufacturing processes specially adapted therefor
06Organic material
74Natural macromolecular material or derivatives thereof
CPC
A61L 27/34
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION, OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES
27Materials for ; grafts or; prostheses or for coating ; grafts or; prostheses
28Materials for coating prostheses
34Macromolecular materials
A61L 27/507
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION, OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES
27Materials for ; grafts or; prostheses or for coating ; grafts or; prostheses
50Materials characterised by their function or physical properties ; , e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
507for artificial blood vessels
A61L 27/60
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION, OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES
27Materials for ; grafts or; prostheses or for coating ; grafts or; prostheses
50Materials characterised by their function or physical properties ; , e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
60Materials for use in artificial skin
B01D 69/10
BPERFORMING OPERATIONS; TRANSPORTING
01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
DSEPARATION
69Semi-permeable membranes for separation processes or apparatus characterised by their form, structure or properties; Manufacturing processes specially adapted therefor
10Supported membranes; Membrane supports
B01D 71/74
BPERFORMING OPERATIONS; TRANSPORTING
01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
DSEPARATION
71Semi-permeable membranes for separation processes or apparatus characterised by the material; Manufacturing processes specially adapted therefor
06Organic material
74Natural macromolecular material or derivatives thereof
Y10T 428/249955
YSECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
10TECHNICAL SUBJECTS COVERED BY FORMER USPC
TTECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
428Stock material or miscellaneous articles
249921Web or sheet containing structurally defined element or component
249953Composite having voids in a component [e.g., porous, cellular, etc.]
249955Void-containing component partially impregnated with adjacent component
Applicants
  • BAXTER INTERNATIONAL INC. [CA]/[US] (AllExceptUS)
  • DELMOTTE, Yves [BE]/[BE] (UsOnly)
  • BELOT, Nathalie [BE]/[BE] (UsOnly)
  • VERMEULEN, Pierre [BE]/[BE] (UsOnly)
  • TASIAUX, Nicole [BE]/[BE] (UsOnly)
Inventors
  • DELMOTTE, Yves
  • BELOT, Nathalie
  • VERMEULEN, Pierre
  • TASIAUX, Nicole
Agents
  • GUTHRIE, Janice
Priority Data
980079604.11.1998BE
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) ELEMENT PROVIDED WITH A FIBRIN LAYER, PREPARATION AND USE THEREOF
(FR) ELEMENT POURVU D'UNE COUCHE DE FIBRINE, SA PREPARATION ET SON UTILISATION
Abstract
(EN)
An element provided with a layer based on fibrin- or fibrinogen-containing material, said element comprising (a) a hydrophobic or substantially hydrophobic support, which has a porous part with a thickness of 0.1 to 5 mm, and whose pores, extending across its thickness have a node spacing of 5 to 100 $g(m)m, one face of said porous part being treated with a compound based on fibrin and/or a fibrinogen-containing material, and (b) a fibrin-based layer covering said treated surface of the support, characterized in that said fibrin-based layer is substantially uniform and homogeneous on said treated surface, and that the fibrin layer and at least the face of the support in contact with the fibrin layer are substantially free of fibrinogen.
(FR)
L'invention concerne un élément pourvu d'une couche à base d'un matériau fibrinogène ou contenant de la fibrine, ledit élément comprenant (a) un support hydrophobe ou sensiblement hydrophobe qui possède une épaisseur comprise entre 0,1 et 5 mm et dont les pores (qui le traversent en épaisseur) ont espacement entre les noeuds compris entre 5 et 100 $g(m)m, une face de ladite partie poreuse ayant été traitée avec un composé à base d'un matériau fibrinogène ou contenant de la fibrine et (b) une couche à base de fibrine recouvrant ladite surface traitée du support et caractérisée en ce qu'elle est sensiblement uniforme et homogène sur toute la surface traitée et en ce que cette couche à base de fibrine et au moins la face du support en contact avec ladite couche sont sensiblement exemptes de fibrinogène.
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