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Machine translation
1. (WO2000025825) DDS COMPOUNDS AND METHOD FOR ASSAYING THE SAME
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2000/025825    International Application No.:    PCT/JP1999/006016
Publication Date: 11.05.2000 International Filing Date: 29.10.1999
Chapter 2 Demand Filed:    29.10.1999    
IPC:
A61K 47/48 (2006.01)
Applicants: DAIICHI PHARMACEUTICAL CO., LTD. [JP/JP]; 14-10, Nihonbashi 3-chome Chuo-ku, Tokyo 103-8234 (JP) (For All Designated States Except US).
SUSAKI, Hiroshi [JP/JP]; (JP) (For US Only).
INOUE, Kazuhiro [JP/JP]; (JP) (For US Only).
KUGA, Hiroshi [JP/JP]; (JP) (For US Only).
IKEDA, Masahiro [JP/JP]; (JP) (For US Only).
SHIOSE, Yoshinobu [JP/JP]; (JP) (For US Only).
KORENAGA, Hiroshi [JP/JP]; (JP) (For US Only)
Inventors: SUSAKI, Hiroshi; (JP).
INOUE, Kazuhiro; (JP).
KUGA, Hiroshi; (JP).
IKEDA, Masahiro; (JP).
SHIOSE, Yoshinobu; (JP).
KORENAGA, Hiroshi; (JP)
Agent: IMAMURA, Masazumi; 5th Floor, KRF Bldg., 5-5, Kyobashi 1-chome Chuo-ku, Tokyo 104-0031 (JP)
Priority Data:
10/310130 30.10.1998 JP
10/329272 19.11.1998 JP
Title (EN) DDS COMPOUNDS AND METHOD FOR ASSAYING THE SAME
(FR) COMPOSES DDS ET PROCEDE DE DOSAGE DE CES COMPOSES
Abstract: front page image
(EN)A method for assaying a DDS compound containing a saccharide compound-modified carboxy C¿1-4? alkyldextran polyalcohol and a drug compound residue bonded to this carboxy C¿1-4? alkyldextran polyalcohol, or a DDS compound wherein a polymer carrier is bonded to a drug compound residue via a spacer containing 2 to 8 amino acids bonded together via peptide bonds, which involves the step of assaying a hydrolysate obtained by treating the DDS compound with peptidase.
(FR)Cette invention se rapporte à un procédé de dosage d'un composé DDS contenant un polyalcool d'alkyldextrane C¿1-4? carboxy modifié par un composé saccharide, ainsi qu'un résidu de composé médicamenteux lié à ce polyalcool d'alkyldextrane C¿1-4? carboxy, ou un composé DDS dans lequel un support polymère est lié à un résidu de composé médicamenteux par l'intermédiaire d'un élément d'espacement contenant 2 à 8 acides aminés liés entre eux par des liaisons peptides, ce procédé consistant à doser un hydrolysat que l'on obtient en traitant le composé DDS avec une peptidase.
Designated States: AE, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BY, CA, CH, CN, CR, CU, CZ, DE, DK, DM, EE, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, NO, NZ, PL, PT, RO, RU, SD, SE, SG, SI, SK, SL, TJ, TM, TR, TT, TZ, UA, UG, US, UZ, VN, YU, ZA, ZW.
African Regional Intellectual Property Organization (GH, GM, KE, LS, MW, SD, SL, SZ, TZ, UG, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, CH, CY, DE, DK, ES, FI, FR, GB, GR, IE, IT, LU, MC, NL, PT, SE)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GW, ML, MR, NE, SN, TD, TG).
Publication Language: Japanese (JA)
Filing Language: Japanese (JA)