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1. (WO2000025793) COMPOSITIONS FOR THE TREATMENT AND PREVENTION OF NEUROLOGICAL AND PATHOPSYCHOLOGICAL DISEASES
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2000/025793    International Application No.:    PCT/EP1999/007688
Publication Date: 11.05.2000 International Filing Date: 13.10.1999
Chapter 2 Demand Filed:    11.04.2000    
IPC:
A61K 31/198 (2006.01), A61K 31/205 (2006.01), A61K 31/519 (2006.01), A61K 31/685 (2006.01), A61K 31/70 (2006.01), A61K 31/7076 (2006.01), A61K 45/06 (2006.01)
Applicants: MERCK PATENT GMBH [DE/DE]; Frankfurter Strasse 250, D-64293 Darmstadt (DE) (For All Designated States Except US).
BUCHHOLZ, Herwig [DE/DE]; (DE) (For US Only).
MEDUSKI, Jerzy, D. [US/US]; (US) (For US Only)
Inventors: BUCHHOLZ, Herwig; (DE).
MEDUSKI, Jerzy, D.; (US)
Common
Representative:
MERCK PATENT GMBH; Frankfurter Strasse 250, D-64293 Darmstadt (DE)
Priority Data:
60/106,230 30.10.1998 US
Title (EN) COMPOSITIONS FOR THE TREATMENT AND PREVENTION OF NEUROLOGICAL AND PATHOPSYCHOLOGICAL DISEASES
(FR) COMPOSITION DE TRAITEMENT ET DE PREVENTION DE TROUBLES NEUROLOGIQUES ET PSYCHOPATHOLOGIQUES
Abstract: front page image
(EN)Compositions comprising one or more active ingredients and, optionally, one or more nutritional substances, solid, liquid and/or semiliquid excipients or auxiliaries, wherein the active ingredients consist of a) a component A consisting of one or more phosphatidylserines, b) a component B consisting of one or more methyl transporters, and c) a component C consisting of one or more compounds selected from methyl and methylene donors, provided that phosphatidylserines and compounds with methyl transporting properties do not form part of component C are well-suited for the treatment and prevention of transmethylation disorders, preferably neurological and pathopsychological diseases.
(FR)Ces compositions comprennent au moins un principe actif, éventuellement au moins une substance nutritive, ainsi que des excipients ou véhicules solides, liquides et/ou semi-liquides, le principe actif étant constitué: a) d'un composant A comprenant au moins une phosphatidylsérine, b) d'un composant B comprenant des transporteurs de méthyle, et c) d'un composant C comprenant au moins un composé choisi parmi des donneurs de méthyle et méthylène, à condition que des phosphatidylsérines et des composés à propriété de transport de méthyle ne fassent pas partie du composant C. Ces compositions sont notamment conçues pour le traitement et la prévention des troubles de la transméthylation, de préférence des maladies neurologiques et psychopathologiques.
Designated States: AE, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BY, CA, CH, CN, CU, CZ, DE, DK, EE, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MD, MG, MK, MN, MW, MX, NO, NZ, PL, PT, RO, RU, SD, SE, SG, SI, SK, SL, TJ, TM, TR, TT, UA, UG, US, UZ, VN, YU, ZA, ZW.
African Regional Intellectual Property Organization (GH, GM, KE, LS, MW, SD, SL, SZ, TZ, UG, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, CH, CY, DE, DK, ES, FI, FR, GB, GR, IE, IT, LU, MC, NL, PT, SE)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)