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1. WO2000025740 - TOPICAL COMPOSITIONS FOR ENHANCING GLUTATHIONE PRODUCTION

Publication Number WO/2000/025740
Publication Date 11.05.2000
International Application No. PCT/US1999/026176
International Filing Date 05.11.1999
IPC
A61K 31/195 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
19Carboxylic acids, e.g. valproic acid
195having an amino group
A61K 31/385 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
33Heterocyclic compounds
38having sulfur as a ring hetero atom
385having two or more sulfur atoms in the same ring
CPC
A61K 31/195
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic, hydroximic acids
19Carboxylic acids, e.g. valproic acid
195having an amino group
A61K 31/385
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
33Heterocyclic compounds
38having sulfur as a ring hetero atom
385having two or more sulfur atoms in the same ring
A61K 8/447
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
8Cosmetics or similar toilet preparations
18characterised by the composition
30containing organic compounds
40containing nitrogen
44Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof
447containing sulfur
A61K 8/4986
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
8Cosmetics or similar toilet preparations
18characterised by the composition
30containing organic compounds
49containing heterocyclic compounds
4986with sulfur as the only hetero atom
A61P 17/16
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
17Drugs for dermatological disorders
16Emollients or protectives, e.g. against radiation
A61Q 17/00
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
QSPECIFIC USE OF COSMETICS OR SIMILAR TOILET PREPARATIONS
17Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
Applicants
  • COLOR ACCESS, INC. [US]/[US]
Inventors
  • MAMMONE, Thomas
  • GAN, David, C.
Agents
  • TSEVDOS, Estelle, J.
Priority Data
09/186,52505.11.1998US
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) TOPICAL COMPOSITIONS FOR ENHANCING GLUTATHIONE PRODUCTION
(FR) COMPOSITIONS TOPIQUES PERMETTANT D'AMELIORER LA PRODUCTION DE GLUTATHION
Abstract
(EN)
The invention provides cosmetic or pharmaceutical compositions for topical application to the skin comprising glutathione-enhancing effective amounts of a glycine compound, a glutamine compound, and a sulfhydryl-containing organic acid, in a cosmetically or pharmaceutically acceptable carrier. The compositions are useful in increasing glutathione synthesis in skin cells, and in treating skin conditions associated with glutathione depletion in skin cells.
(FR)
L'invention concerne des compositions cosmétiques ou pharmaceutiques destinées à une application topique sur la peau. Ces compositions comprennent des quantités d'un composé de glycine, d'un composé de glutamine et d'un acide organique contenant du sulfhydryle, dans un excipient cosmétiquement ou pharmaceutiquement acceptable, lesquelles quantités sont efficaces pour augmenter la production de glutathion. Ces compositions servent à augmenter la synthèse du glutathion dans les cellules de la peau et à traiter des états pathologiques de la peau associés à une raréfaction du glutathion dans les cellules de la peau.
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