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Machine translation
1. (WO2000024416) REMEDIES FOR BONE METABOLIC ERRORS
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2000/024416    International Application No.:    PCT/JP1999/005963
Publication Date: 04.05.2000 International Filing Date: 28.10.1999
Chapter 2 Demand Filed:    28.10.1999    
IPC:
A61K 38/00 (2006.01), A61K 38/17 (2006.01), A61K 47/36 (2006.01), C07K 14/705 (2006.01)
Applicants: SNOW BRAND MILK PRODUCTS CO., LTD. [JP/JP]; 1-1, Naebocho 6-chome,Higashi-ku Sapporo-shi, Hokkaido 065-0043 (JP) (For All Designated States Except US).
SANKYO CO., LTD. [JP/JP]; 2-58, Hiromachi 1-chome Shinagawa-ku, Tokyo 140-8710 (JP) (For All Designated States Except US).
MOCHIZUKI, Shinichi [JP/JP]; (JP) (For US Only).
FUJISE, Nobuaki [JP/JP]; (JP) (For US Only).
MASUYAMA, Chiharu [JP/JP]; (JP) (For US Only).
TSUDA, Eisuke [JP/JP]; (JP) (For US Only).
HIGASHIO, Kanji [JP/JP]; (JP) (For US Only)
Inventors: MOCHIZUKI, Shinichi; (JP).
FUJISE, Nobuaki; (JP).
MASUYAMA, Chiharu; (JP).
TSUDA, Eisuke; (JP).
HIGASHIO, Kanji; (JP)
Agent: FUJINO, Seiya; Mitsuhama Building 8th floor 2-1, Yotsuya 1-chome Shinjuku-ku Tokyo 160-0004 (JP)
Priority Data:
10-322874 28.10.1998 JP
Title (EN) REMEDIES FOR BONE METABOLIC ERRORS
(FR) AGENTS THERAPEUTIQUES POUR DEFORMATIONS OSSEUSES
Abstract: front page image
(EN)Novel remedies for bone metabolic errors. These remedies comprise at least one member selected from the group consisting of osteoclastogenesis inhibitory factor (OCIF), analogs thereof and variants thereof and polysaccharides or derivatives thereof. As the polysaccharides or derivatives thereof, use may be made of heparin, dextran sulfate, etc. These remedies have excellent therapeutic effects on bone metabolic errors such as osteoporosis, hypercalcemia and rheumatoid arthritis and can sustain the activities over a long time, which makes them highly useful as drugs.
(FR)L'invention concerne de nouveaux agents thérapeutiques permettant de traiter les déformations osseuses. Ces agents thérapeutiques comprennent au moins un élément sélectionné dans le groupe constitué d'un facteur inhibiteur d'ostéoclastogenèse (OCIF), ses analogues, ses variantes, ses polysaccharides ou ses dérivés. Les polysaccharides ou dérivés précités peuvent être l'héparine, le dextran-sulfate, etc. Ces agents thérapeutiques agissent de manière efficace sur les déformations osseuses telles que l'ostéoporose, l'hypercalcémie et la polyarthrite rhumatoïde et leur action est durable, ce qui en fait des médicaments très prisés.
Designated States: AU, BR, CA, CN, CZ, HU, ID, IL, IN, JP, KR, MX, NO, NZ, PL, RU, TR, US, ZA.
European Patent Office (AT, BE, CH, CY, DE, DK, ES, FI, FR, GB, GR, IE, IT, LU, MC, NL, PT, SE).
Publication Language: Japanese (JA)
Filing Language: Japanese (JA)