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1. WO2000018792 - SOLID PHASE SYNTHESIS, WHEREBY THE SOLID PHASE CONSISTS OF TWO DIFFERENT SUBSTRATES

Publication Number WO/2000/018792
Publication Date 06.04.2000
International Application No. PCT/EP1999/007203
International Filing Date 29.09.1999
Chapter 2 Demand Filed 19.04.2000
IPC
B01J 19/00 2006.1
BPERFORMING OPERATIONS; TRANSPORTING
01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
19Chemical, physical or physico-chemical processes in general; Their relevant apparatus
C07B 61/00 2006.1
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
BGENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
61Other general methods
C07H 21/00 2006.1
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
21Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
C07K 1/04 2006.1
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
1General processes for the preparation of peptides
04on carriers
CPC
B01J 19/0046
BPERFORMING OPERATIONS; TRANSPORTING
01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
19Chemical, physical or physico-chemical processes in general; Their relevant apparatus
0046Sequential or parallel reactions, e.g. for the synthesis of polypeptides or polynucleotides; Apparatus and devices for combinatorial chemistry or for making molecular arrays
B01J 2219/00283
BPERFORMING OPERATIONS; TRANSPORTING
01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
2219Chemical, physical or physico-chemical processes in general; Their relevant apparatus
00274Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
00277Apparatus
00279Features relating to reactor vessels
00281Individual reactor vessels
00283Reactor vessels with top opening
B01J 2219/00315
BPERFORMING OPERATIONS; TRANSPORTING
01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
2219Chemical, physical or physico-chemical processes in general; Their relevant apparatus
00274Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
00277Apparatus
00279Features relating to reactor vessels
00306Reactor vessels in a multiple arrangement
00313the reactor vessels being formed by arrays of wells in blocks
00315Microtiter plates
B01J 2219/00351
BPERFORMING OPERATIONS; TRANSPORTING
01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
2219Chemical, physical or physico-chemical processes in general; Their relevant apparatus
00274Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
00277Apparatus
00351Means for dispensing and evacuation of reagents
B01J 2219/00373
BPERFORMING OPERATIONS; TRANSPORTING
01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
2219Chemical, physical or physico-chemical processes in general; Their relevant apparatus
00274Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
00277Apparatus
00351Means for dispensing and evacuation of reagents
00373Hollow needles
B01J 2219/0047
BPERFORMING OPERATIONS; TRANSPORTING
01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
2219Chemical, physical or physico-chemical processes in general; Their relevant apparatus
00274Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
00277Apparatus
00457Dispensing or evacuation of the solid phase support
0047Pins
Applicants
  • MOLECULAR MACHINES & INDUSTRIES GMBH [DE]/[DE] (AllExceptUS)
  • SEEGER, Stefan [DE]/[DE] (UsOnly)
Inventors
  • SEEGER, Stefan
Agents
  • KINDLER, Matthias
Priority Data
198 44 988.730.09.1998DE
Publication Language German (de)
Filing Language German (DE)
Designated States
Title
(DE) FESTPHASENSYNTHESE, WOBEI DIE FESTPHASE AUS ZWEI UNTERSCHIEDLICHEN SUBSTRATEN BESTEHT
(EN) SOLID PHASE SYNTHESIS, WHEREBY THE SOLID PHASE CONSISTS OF TWO DIFFERENT SUBSTRATES
(FR) SYNTHESE SUR PHASE SOLIDE, LA PHASE SOLIDE COMPRENANT DEUX SUBSTRATS DIFFERENTS
Abstract
(DE) Die Erfindung betrifft die Synthese von Substanzen an einer Festphase, wobei die Festphase aus zwei unterschiedlichen Substraten besteht, ein hierfür geeignetes Reaktionssystem sowie ein Verfahren umfassend eine Festphasensynthese und ein analytisches Verfahren, bei dem sowohl die chemische Struktur als auch die biologischen Eigenschaften der synthetisierten Substanz analysiert werden. Die erfindungsgemäße Festphasensynthese von Substanzen in einem eine flüssige Phase enthaltenden Reaktionsgefäß ist dadurch gekennzeichnet, daß die Festphase zur Synthese ein in der flüssigen Phase reversibel eingeführtes Substrat und ganz oder teilweise die Gefäßwand des Reaktionsgefässes umfaßt.
(EN) The invention relates to the synthesis of substances on a solid phase consisting of two different substrates, to a suitable reaction system and to a method comprising solid-phase synthesis and an analytical process during which the chemical structure and the biological properties of the synthesised substance are analysed. The inventive solid-phase synthesis of substances in a reaction vessel containing a liquid phase is characterised in that the solid phase for the synthesis comprises a substrate that is reversibly added in the liquid phase and the wall of the reaction vessel in its entirety or in part.
(FR) L'invention concerne la synthèse de substances sur une phase solide, cette dernière comprenant deux substrats différents, ainsi qu'un système de réaction approprié et un procédé comprenant une synthèse à l'état solide et un procédé analytique, selon lequel on analyse aussi bien la structure chimique que les propriétés biologiques de la substance synthétisée. La synthèse à l'état solide de substances selon l'invention, dans un récipient de réaction contenant une phase liquide, se caractérise en ce que la phase solide requise pour la synthèse, entoure un substrat introduit de manière réversible dans la phase liquide, ainsi que la totalité ou une partie de la paroi du récipient de réaction.
Related patent documents
US09806381This application is not viewable in PATENTSCOPE because the national phase entry has not been published yet or the national entry is issued from a country that does not share data with WIPO or there is a formatting issue or an unavailability of the application.
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