Processing

Please wait...

Settings

Settings

Goto Application

1. WO2000016769 - ACTIVE ENANTIOMER OF RAR$g(g)-SPECIFIC AGONIST

Publication Number WO/2000/016769
Publication Date 30.03.2000
International Application No. PCT/US1999/021920
International Filing Date 21.09.1999
Chapter 2 Demand Filed 17.04.2000
IPC
C07C 235/16 2006.01
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
CACYCLIC OR CARBOCYCLIC COMPOUNDS
235Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms
02having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton
04the carbon skeleton being acyclic and saturated
16having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a six-membered aromatic ring
CPC
A61K 31/196
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic, hydroximic acids
19Carboxylic acids, e.g. valproic acid
195having an amino group
196the amino group being directly attached to a ring, e.g. anthranilic acid, mefenamic acid, diclofenac, chlorambucil
A61P 17/00
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
17Drugs for dermatological disorders
A61P 17/06
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
17Drugs for dermatological disorders
06Antipsoriatics
A61P 17/12
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
17Drugs for dermatological disorders
12Keratolytics, e.g. wart or anti-corn preparations
A61P 35/00
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
35Antineoplastic agents
A61P 43/00
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
43Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Applicants
  • BRISTOL-MYERS SQUIBB COMPANY [US]/[US]
Inventors
  • BELEMA, Makonen
  • ZUSI, Fred, C.
  • TRAMPOSCH, Kenneth, M.
Agents
  • MORSE, David, M.
Priority Data
60/101,74724.09.1998US
60/125,89124.03.1999US
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) ACTIVE ENANTIOMER OF RAR$g(g)-SPECIFIC AGONIST
(FR) ENANTIOMERE ACTIF D'AGONISTE SPECIFIQUE VIS-A-VIS DU RAR$g(g)
Abstract
(EN)
Disclosed is the (R)-enantiomer of formula (I), which has unexpectedly been found to possess all of the biological activity of the racemic compound disclosed in the prior art as an RAR$g(g)-specific agonist.
(FR)
L'invention concerne l'énantiomère-(R) représenté par la formule (I). De manière inattendue, il est apparu que cet énantiomère possédait tout l'éventail de l'activité biologique du composé racémique connu dans l'état actuel de la technique comme agoniste spécifique vis-à-vis du RAR$g(g).
Latest bibliographic data on file with the International Bureau