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1. WO2000015787 - GENES ENCODING FOR THE HUMAN AND MURINE DEATH INDUCER-OBLITERATOR-1

Publication Number WO/2000/015787
Publication Date 23.03.2000
International Application No. PCT/GB1999/003019
International Filing Date 10.09.1999
Chapter 2 Demand Filed 10.04.2000
IPC
A61K 38/00 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
38Medicinal preparations containing peptides
A61K 48/00 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
48Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
C07K 14/47 2006.01
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
14Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
435from animals; from humans
46from vertebrates
47from mammals
C07K 16/18 2006.01
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
16Immunoglobulins, e.g. monoclonal or polyclonal antibodies
18against material from animals or humans
CPC
A61K 38/00
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
38Medicinal preparations containing peptides
A61K 48/00
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
48Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
A61P 17/00
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
17Drugs for dermatological disorders
A61P 29/00
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
29Non-central analgesic, antipyretic or anti-inflammatory agents, e.g antirheumatic agents; Non-steroidal anti-inflammatory drugs (NSAIDs)
A61P 3/10
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
3Drugs for disorders of the metabolism
08for glucose homeostasis
10for hyperglycaemia, e.g. antidiabetics
A61P 35/00
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
35Antineoplastic agents
Applicants
  • CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS [ES]/[ES] (AllExceptUS)
  • ALONSO, Carlos Martinez [ES]/[ES] (UsOnly)
  • DOMINGO, David Garcia [ES]/[ES] (UsOnly)
  • GRANDIEN, Alf [SE]/[SE] (UsOnly)
  • LEONARDO, Esther [ES]/[ES] (UsOnly)
  • MARTINEZ, Pedro [ES]/[ES] (UsOnly)
Inventors
  • ALONSO, Carlos Martinez
  • DOMINGO, David Garcia
  • GRANDIEN, Alf
  • LEONARDO, Esther
  • MARTINEZ, Pedro
Agents
  • BANNERMAN, D., G.
Priority Data
60/100,87317.09.1998US
9803069-510.09.1998SE
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) GENES ENCODING FOR THE HUMAN AND MURINE DEATH INDUCER-OBLITERATOR-1
(FR) GENES CODANT POUR L'ANNULATEUR-INDUCTEUR-1 DE MORT CELLULAIRE D'ORIGINE HUMAINE OU MURINE
Abstract
(EN)
The present invention relates to a novel DNA sequence that codes for expression of a human Death Inducer-Obliterator 1 (DIO-1)gene and the polypeptide derived from the DNA sequence. Expression vectors containing such sequences and host cells transformed with such expression vectors are also disclosed, as are methods for the expression of the novel DIO-1 polypeptide of the invention, and uses thereof.
(FR)
La présente invention se rapporte à une nouvelle séquence d'ADN qui code pour l'expression d'un gène humain annulateur-inducteur de mort cellulaire 1 (DIO-1 $i(Death Inducer-Obliterator) 1), ainsi qu'au polypeptide dérivé de ladite séquence d'ADN. L'invention se rapporte également à des vecteurs d'expression contenant de telles séquences et à des cellules hôtes transformées par de tels vecteurs d'expression. L'invention se rapporte enfin à des méthodes d'expression du nouveau polypeptide DIO-1 et à des utilisations de ce dernier.
Also published as
NZ510365
US09787016
Latest bibliographic data on file with the International Bureau