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1. WO2000014545 - MULTIHUED LABELS

Publication Number WO/2000/014545
Publication Date 16.03.2000
International Application No. PCT/US1999/019708
International Filing Date 30.08.1999
Chapter 2 Demand Filed 31.03.2000
IPC
G PHYSICS
01
MEASURING; TESTING
N
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
33
Investigating or analysing materials by specific methods not covered by groups G01N1/-G01N31/131
48
Biological material, e.g. blood, urine; Haemocytometers
50
Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
53
Immunoassay; Biospecific binding assay; Materials therefor
543
with an insoluble carrier for immobilising immunochemicals
G PHYSICS
01
MEASURING; TESTING
N
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
33
Investigating or analysing materials by specific methods not covered by groups G01N1/-G01N31/131
48
Biological material, e.g. blood, urine; Haemocytometers
50
Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
58
involving labelled substances
G PHYSICS
01
MEASURING; TESTING
N
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
33
Investigating or analysing materials by specific methods not covered by groups G01N1/-G01N31/131
48
Biological material, e.g. blood, urine; Haemocytometers
50
Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
68
involving proteins, peptides or amino acids
G01N 33/543 (2006.01)
G01N 33/58 (2006.01)
G01N 33/68 (2006.01)
CPC
G01N 33/54313
G01N 33/585
G01N 33/68
Applicants
  • TRELLIS BIOINFORMATICS, INC. [US/US]; 1489 Webster Street #521 San Francisco, CA 94115, US
Inventors
  • KAUVAR, Lawrence, M.; US
  • SEDAT, John; US
Agents
  • MURASHIGE, Kate, H. ; Morrison & Foerster LLP 2000 Pennsylvania Avenue, N.W. Washington, DC 20006-1888, US
  • GOLDIN Douglas Michael; J.A. Kemp & Co 14 South Square, Gray's Inn, London WC1R 5LX, GB
Priority Data
09/146,98403.09.1998US
09/332,61314.06.1999US
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) MULTIHUED LABELS
(FR) ETIQUETTES A NUANCES MULTIPLES
Abstract
(EN)
Particulate labels that can be individually identified comprise particulate supports to which are bound at least two distinguishable signal-generating moieties, such as fluorophores emitting at different wavelengths, which signals are detectable and measurable $(in situ). By varying the ratio and/or amounts of the signal-generating moieties, a multiplicity of different and distinguishable labels is obtained. Each different label can then be coupled to a different reagent and the individual interactions of each reagent with a target observed in parallel.
(FR)
L'invention concerne des étiquettes particulaires que l'on peut identifier individuellement, comportant des supports particulaires, auxquels sont liés au moins deux groupes caractéristiques distinguables générateurs de signaux, tels que des fluorogènes émettant à des longueurs d'onde différentes. Lesdits signaux sont détectables et mesurables sur place. En variant le rapport et/ou les quantités de groupes caractéristiques générateurs de signaux, on obtient un grand nombre d'étiquettes différentes et distinguables. On peut alors coupler chaque étiquette différente à un réactif différent et les interactions individuelles de chaque réactif à une cible observée parallèlement.
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