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1. WO2000002620 - METHOD AND APPARATUS FOR ELECTRICALLY ASSISTED TOPICAL DELIVERY OF AGENTS FOR COSMETIC APPLICATIONS

Publication Number WO/2000/002620
Publication Date 20.01.2000
International Application No. PCT/US1999/015754
International Filing Date 13.07.1999
Chapter 2 Demand Filed 11.02.2000
IPC
A61N 1/32 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
1Electrotherapy; Circuits therefor
18Applying electric currents by contact electrodes
32alternating or intermittent currents
CPC
A61N 1/0424
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
1Electrotherapy; Circuits therefor
02Details
04Electrodes
0404for external use
0408Use-related aspects
0412Specially adapted for transcutaneous electroporation, e.g. including drug reservoirs
0416Anode and cathode
0424Shape of the electrode
A61N 1/0428
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
1Electrotherapy; Circuits therefor
02Details
04Electrodes
0404for external use
0408Use-related aspects
0428Specially adapted for iontophoresis, e.g. AC, DC or including drug reservoirs
A61N 1/0436
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
1Electrotherapy; Circuits therefor
02Details
04Electrodes
0404for external use
0408Use-related aspects
0428Specially adapted for iontophoresis, e.g. AC, DC or including drug reservoirs
0432Anode and cathode
0436Material of the electrode
A61N 1/0448
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
1Electrotherapy; Circuits therefor
02Details
04Electrodes
0404for external use
0408Use-related aspects
0428Specially adapted for iontophoresis, e.g. AC, DC or including drug reservoirs
0448Drug reservoir
A61N 1/0468
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
1Electrotherapy; Circuits therefor
02Details
04Electrodes
0404for external use
0408Use-related aspects
0468Specially adapted for promoting wound healing
A61N 1/325
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
1Electrotherapy; Circuits therefor
18Applying electric currents by contact electrodes
32alternating or intermittent currents
325for iontophoresis, i.e. transfer of media in ionic state by an electromotoric force into the body
Applicants
  • GENETRONICS, INC. [US]/[US] (AllExceptUS)
  • ZHANG, Lei [CN]/[US] (UsOnly)
  • HOFMANN, Gunter, A. [US]/[US] (UsOnly)
Inventors
  • ZHANG, Lei
  • HOFMANN, Gunter, A.
Agents
  • HAILE, Lisa, A.
Priority Data
60/092,54113.07.1998US
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) METHOD AND APPARATUS FOR ELECTRICALLY ASSISTED TOPICAL DELIVERY OF AGENTS FOR COSMETIC APPLICATIONS
(FR) PROCEDE ET APPAREIL D'APPORT TOPIQUE DOTE D'UNE ASSISTANCE ELECTRIQUE D'AGENTS DESTINES A DES APPLICATIONS COSMETIQUES
Abstract
(EN)
The present invention is based upon the development of a method for cosmetic delivery of L ascorbic acid, containing compositions to the layer of the skin wherein collagen formation takes place to enhance production of collagen thereby combat some of the effects of aging, and oxy-radical damage on the skin. Sufficient electric pulses applied to a region of skin surface temporarily create new pathways through the lipid skin barrier, thereby delivering an L ascorbic acid containing composition through the lipid skin barrier, and enhancing production of collagen in the region of the skin so treated. A hand held electrical pulsing apparatus (4), optionally table top adaptable, and methods of use for cosmetic treatment of degenerative skin conditions are provided by the invention.
(FR)
La présente invention est fondée sur la mise au point d'un procédé d'apport à visée cosmétique de compositions contenant de l'acide ascorbique L sur la couche de la peau où s'effectue la formation du collagène pour améliorer la production de collagène et combattre certains effets du vieillissement et des dommages provoqués par les radicaux hydroxy sur la peau. Des impulsions électriques suffisantes sont appliquées sur une région superficielle de la peau et créent momentanément de nouveaux passages à travers la barrière lipidique de la peau, ceci ayant pour effet d'apporter une composition contenant de l'acide ascorbique L à travers la barrière lipidique de la peau et d'améliorer la production de collagène dans la région cutanée traitée de la sorte. Un appareil portatif (4) produisant des impulsions électriques, facultativement adaptable sur une table, et des procédés d'utilisation destinés au traitement cosmétique des états cutanés dégénératifs sont décrits dans la présente invention.
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