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1. (WO2000000238) TOPOISOMERASE INHIBITORS FOR PREVENTION OF RESTENOSIS
Latest bibliographic data on file with the International Bureau

Pub. No.: WO/2000/000238 International Application No.: PCT/US1999/014386
Publication Date: 06.01.2000 International Filing Date: 24.06.1999
Chapter 2 Demand Filed: 18.01.2000
IPC:
A61K 31/47 (2006.01) ,A61K 31/57 (2006.01) ,A61L 29/16 (2006.01) ,A61L 31/16 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
33
Heterocyclic compounds
395
having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
435
having six-membered rings with one nitrogen as the only ring hetero atom
47
Quinolines; Isoquinolines
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
56
Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
57
substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane, progesterone
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
L
METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION, OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES
29
Materials for catheters or for coating catheters
14
Materials characterised by their function or physical properties
16
Biologically active materials, e.g. therapeutic substances
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
L
METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION, OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES
31
Materials for other surgical articles
14
Materials characterised by their function or physical properties
16
Biologically active materials, e.g. therapeutic substances
Applicants:
QUANAM MEDICAL CORPORATION [US/US]; 2255 Martin Avenue Santa Clara, CA 95050, US
Inventors:
EURY, Robert; US
ALVARADO, Angelica; US
POMERANTSEVA, Irina; US
FROIX, Michael; US
Agent:
MOHR, Judy, M. ; Dehlinger & Associates P.O. Box 60850 Palo Alto, CA 94306-0850, US
VOSSIUS & PARTNER (No. 31); Siebertstrasse 4 D-81675 München, DE
Priority Data:
60/090,76426.06.1998US
Title (EN) TOPOISOMERASE INHIBITORS FOR PREVENTION OF RESTENOSIS
(FR) INHIBITEURS DE TOPOISOMERASE PERMETTANT DE PREVENIR LA RESTENOSE
Abstract:
(EN) A method of inhibiting cellular proliferation associated with a hyperproliferative condition, such as restenosis, is described. The method includes administering a topoisomerase inhibitor. A stent for local administration of the topoisomerase inhibitor is also described.
(FR) Cette invention concerne un procédé permettant d'inhiber la prolifération cellulaire associée à des conditions d'hyper-prolifération, telles que la resténose. Ce procédé consiste à administrer un inhibiteur de topoisomérase. Cette invention concerne également un extenseur servant à l'administration locale de l'inhibiteur de topoisomérase.
Designated States: CA, JP
European Patent Office (AT, BE, CH, CY, DE, DK, ES, FI, FR, GB, GR, IE, IT, LU, MC, NL, PT, SE)
Publication Language: English (EN)
Filing Language: English (EN)
Also published as:
EP1087801JP2002519335 CA2335842