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1. WO1999067265 - 2-(PURIN-9-YL)-TETRAHYDROFURAN-3,4-DIOL DERIVATIVES

Publication Number WO/1999/067265
Publication Date 29.12.1999
International Application No. PCT/EP1999/004269
International Filing Date 23.06.1999
Chapter 2 Demand Filed 17.12.1999
IPC
A61K 31/7076 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
70Carbohydrates; Sugars; Derivatives thereof
7042Compounds having saccharide radicals and heterocyclic rings
7052having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
706containing six-membered rings with nitrogen as a ring hetero atom
7064containing condensed or non-condensed pyrimidines
7076containing purines, e.g. adenosine, adenylic acid
C07H 7/06 2006.1
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
7Compounds containing non-saccharide radicals linked to saccharide radicals by a carbon-to-carbon bond
06Heterocyclic radicals
C07H 19/16 2006.1
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
19Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro derivatives thereof
02sharing nitrogen
04Heterocyclic radicals containing only nitrogen as ring hetero atom
16Purine radicals
CPC
A61K 31/7076
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
70Carbohydrates; Sugars; Derivatives thereof
7042Compounds having saccharide radicals and heterocyclic rings
7052having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
706containing six-membered rings with nitrogen as a ring hetero atom
7064containing condensed or non-condensed pyrimidines
7076containing purines, e.g. adenosine, adenylic acid
A61P 11/06
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
11Drugs for disorders of the respiratory system
06Antiasthmatics
A61P 29/00
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
29Non-central analgesic, antipyretic or anti-inflammatory agents, e.g antirheumatic agents; Non-steroidal anti-inflammatory drugs (NSAIDs)
A61P 37/06
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
37Drugs for immunological or allergic disorders
02Immunomodulators
06Immunosuppressants, e.g. drugs for graft rejection
A61P 43/00
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
43Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
C07H 1/00
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
1Processes for the preparation of sugar derivatives
Applicants
  • GLAXO GROUP LIMITED [GB]/[GB] (AllExceptUS)
  • ALLEN, David, George [GB]/[GB] (UsOnly)
  • CHAN, Chuen [GB]/[GB] (UsOnly)
  • COUSINS, Richard, Peter, Charles [GB]/[GB] (UsOnly)
  • COX, Brian [GB]/[GB] (UsOnly)
  • GEDEN, Joanna, Victoria [GB]/[GB] (UsOnly)
  • HOBBS, Heather [GB]/[GB] (UsOnly)
  • KEELING, Suzanne, Elaine [GB]/[GB] (UsOnly)
  • REDGRAVE, Alison, Judith [GB]/[GB] (UsOnly)
  • ROPER, Thomas, Davis, IV [US]/[US] (UsOnly)
  • XIE, Shiping [CN]/[US] (UsOnly)
Inventors
  • ALLEN, David, George
  • CHAN, Chuen
  • COUSINS, Richard, Peter, Charles
  • COX, Brian
  • GEDEN, Joanna, Victoria
  • HOBBS, Heather
  • KEELING, Suzanne, Elaine
  • REDGRAVE, Alison, Judith
  • ROPER, Thomas, Davis, IV
  • XIE, Shiping
Agents
  • TEUTEN, Andrew, J.
Priority Data
9813538.723.06.1998GB
9909482.323.04.1999GB
Publication Language English (en)
Filing Language English (EN)
Designated States
Title
(EN) 2-(PURIN-9-YL)-TETRAHYDROFURAN-3,4-DIOL DERIVATIVES
(FR) DERIVES DU 2-(PURIN-9-YL)-TETRAHYDROFURAN-3,4 DIOL
Abstract
(EN) There are provided according to the invention, novel compounds of formula (I) wherein R1, R2 and R3 are as defined in the specification, processes for preparing them, formulations containing them and their use in therapy for the treatment of inflammatory diseases.
(FR) L'invention porte sur de nouveaux composés de formule (I) dans laquelle: R1, R2 et R3 sont définis dans la description, sur leurs procédés d'obtention, sur des préparations les contenant, et sur leur utilisation pour le traitement de maladies à caractère inflammatoire.
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