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1. WO1999055896 - A NEW GLUCOSE-6-PHOSPHATE TRANSLOCASE INHIBITOR L 970885 FROM AN ACTINOMYCETE SP., AND CHEMICAL DERIVATIVES THEREOF, A PROCESS FOR THE PREPARATION AND THEIR USE AS PHARMACEUTICALS

Publication Number WO/1999/055896
Publication Date 04.11.1999
International Application No. PCT/EP1999/002671
International Filing Date 21.04.1999
Chapter 2 Demand Filed 16.11.1999
IPC
C12P 1/06 2006.01
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
1Preparation of compounds or compositions, not provided for in groups C12P3/-C12P39/121; General processes for the preparation of compounds or compositions by using microorganisms or enzymes
06by using actinomycetales
C12P 15/00 2006.01
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
15Preparation of compounds containing at least three condensed carbocyclic rings
CPC
C12P 1/06
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
1Preparation of compounds or compositions, not provided for in groups C12P3/00 - C12P39/00, by using microorganisms or enzymes
06by using actinomycetales
C12P 15/00
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
15Preparation of compounds containing at least three condensed carbocyclic rings
C12R 1/04
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
RPROCESSES USING MICROORGANISMS
1Processes using microorganisms
01using bacteria or actinomycetales
04Actinomyces
Applicants
  • AVENTIS PHARMA DEUTSCHLAND GMBH [DE]/[DE] (AllExceptUS)
  • SWAMY, Keshavapura, Hosamane, Sreedhara [IN]/[IN] (UsOnly)
  • RAMAKRISHNA, Nirogi, Venkata, Satya [IN]/[IN] (UsOnly)
  • VIJAYA KUMAR, Erra, Koteswara, Satya [IN]/[IN] (UsOnly)
  • MORE, Tulsidas, Sitaram [IN]/[IN] (UsOnly)
  • TANPURE, Rajendra, Prakash [IN]/[IN] (UsOnly)
  • TARE, Swati, Dhananjay [IN]/[IN] (UsOnly)
  • SHANBHAG, Prashant, Venkatesh [IN]/[IN] (UsOnly)
  • BHAT, Ravi, Gajanan [IN]/[IN] (UsOnly)
Inventors
  • SWAMY, Keshavapura, Hosamane, Sreedhara
  • RAMAKRISHNA, Nirogi, Venkata, Satya
  • VIJAYA KUMAR, Erra, Koteswara, Satya
  • MORE, Tulsidas, Sitaram
  • TANPURE, Rajendra, Prakash
  • TARE, Swati, Dhananjay
  • SHANBHAG, Prashant, Venkatesh
  • BHAT, Ravi, Gajanan
Priority Data
98107631.827.04.1998EP
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) A NEW GLUCOSE-6-PHOSPHATE TRANSLOCASE INHIBITOR L 970885 FROM AN ACTINOMYCETE SP., AND CHEMICAL DERIVATIVES THEREOF, A PROCESS FOR THE PREPARATION AND THEIR USE AS PHARMACEUTICALS
(FR) NOUVEL INHIBITEUR L 970885 DE GLUCOSE-6-PHOSPHATE TRANSLOCASE PROVENANT D'UN ACTINOMYCETE sp., SES DERIVES CHIMIQUES, SON PROCEDE DE PREPARATION ET SON UTILISATION COMME PRODUIT PHARMACEUTIQUE
Abstract
(EN)
The present invention relates to a novel glucose-6-phosphate translocase inhibitor L 970885, which is produced by an Actinomycete sp. (culture number HIL-000337) during fermentation, a process for its preparation, to chemical derivatives derived from compound L 970885, to the use of compound L 970885 and derivatives derived therefrom and pharmacological active substances, as medicament and, in particular, for the treatment of diabetes mellitus, and to an Actinomycete sp. HIL-000337 (DSM 11992) for producing the abovementioned compound L 970885.
(FR)
La présente invention concerne un nouvel inhibiteur L 970885 de glucose-6-phosphate translocase produit par un Actinomycète sp. (numéro de culture HIL-000337) lors de sa fermentation; son procédé de préparation; des dérivés chimiques provenant du composé L 970885; l'utilisation du composé L 970885 et de ses dérivés et des substances pharmacologiques actives comme médicaments, notamment pour le traitement du diabète sucré. L'invention concerne également un Actinomycète sp. HIL-000337 (DSM 11992) destiné à la production du composé mentionné ci-dessus L 970885.
Also published as
Latest bibliographic data on file with the International Bureau