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1. (WO1999051241) CALCILYTIC COMPOUNDS AND METHOD OF USE
Latest bibliographic data on file with the International Bureau   

Pub. No.: WO/1999/051241 International Application No.: PCT/US1999/007760
Publication Date: 14.10.1999 International Filing Date: 08.04.1999
Chapter 2 Demand Filed: 28.10.1999
IPC:
C07C 255/54 (2006.01) ,C07D 213/38 (2006.01) ,C07D 215/12 (2006.01) ,C07D 217/14 (2006.01) ,C07D 307/79 (2006.01)
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
C
ACYCLIC OR CARBOCYCLIC COMPOUNDS
255
Carboxylic acid nitriles
49
having cyano groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
54
containing cyano groups and etherified hydroxy groups bound to the carbon skeleton
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
D
HETEROCYCLIC COMPOUNDS
213
Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
02
having three double bonds between ring members or between ring members and non-ring members
04
having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
24
with substituted hydrocarbon radicals attached to ring carbon atoms
36
Radicals substituted by singly-bound nitrogen atoms
38
having only hydrogen or hydrocarbon radicals attached to the substituent nitrogen atom
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
D
HETEROCYCLIC COMPOUNDS
215
Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
02
having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
12
with substituted hydrocarbon radicals attached to ring carbon atoms
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
D
HETEROCYCLIC COMPOUNDS
217
Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
12
with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring
14
other than aralkyl radicals
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
D
HETEROCYCLIC COMPOUNDS
307
Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
77
ortho- or peri-condensed with carbocyclic rings or ring systems
78
Benzo [b] furans; Hydrogenated benzo [b] furans
79
with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
Applicants:
BHATNAGAR, Pradip, Kumar [US/US]; US (UsOnly)
CALLAHAN, James, Francis [US/US]; US (UsOnly)
DEL MAR, Eric, G. [US/US]; US (UsOnly)
LAGO, Maria, Amparo [ES/US]; US (UsOnly)
SMITHKLINE BEECHAM CORPORATION [US/US]; One Franklin Plaza Philadelphia, PA 19103, US (AllExceptUS)
NPS PHARMACEUTICALS, INC. [US/US]; 420 Chipeta Way Salt Lake City, UT 84108, US (AllExceptUS)
Inventors:
BHATNAGAR, Pradip, Kumar; US
CALLAHAN, James, Francis; US
DEL MAR, Eric, G.; US
LAGO, Maria, Amparo; US
Agent:
SIMON, Soma, G. ; SmithKline Beecham Corporation Corporate Intellectual Property, UW2220 709 Swedeland Road P.O. Box 1539 King of Prussia, PA 19406-0939, US
Priority Data:
60/081,08708.04.1998US
Title (EN) CALCILYTIC COMPOUNDS AND METHOD OF USE
(FR) COMPOSES CALCILYTIQUES ET LEUR UTILISATION
Abstract:
(EN) Calcilytic compounds and compositions and their use in treating abnormal bone or mineral homeostasis.
(FR) La présente invention concerne des composés et des compositions calcilytiques d'un type nouveau ainsi que leur utilisation pour le traitement de l'homéostasie minérale et osseuse anormale.
Designated States: AE, AL, AU, BA, BB, BG, BR, CA, CN, CZ, EE, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KP, KR, LC, LK, LR, LT, LV, MG, MK, MN, MX, NO, NZ, PL, RO, SG, SI, SK, SL, TR, TT, UA, US, UZ, VN, YU, ZA
African Regional Intellectual Property Organization (ARIPO) (GH, GM, KE, LS, MW, SD, SL, SZ, UG, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (EPO) (AT, BE, CH, CY, DE, DK, ES, FI, FR, GB, GR, IE, IT, LU, MC, NL, PT, SE)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GW, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)