WIPO logo
Mobile | Deutsch | Español | Français | 日本語 | 한국어 | Português | Русский | 中文 | العربية |
PATENTSCOPE

Search International and National Patent Collections
World Intellectual Property Organization
Search
 
Browse
 
Translate
 
Options
 
News
 
Login
 
Help
 
Machine translation
1. (WO1999042596) PHOSPHODIESTERASE 10
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/1999/042596    International Application No.:    PCT/US1999/003879
Publication Date: 26.08.1999 International Filing Date: 23.02.1999
Chapter 2 Demand Filed:    22.09.1999    
IPC:
A61K 38/00 (2006.01), C12N 9/16 (2006.01)
Applicants: ICOS CORPORATION [US/US]; 22021 20th Avenue, S.E. Bothell, WA 98021 (US)
Inventors: LOUGHNEY, Kate; (US)
Agent: WILLIAMS, Joseph, A., Jr.; Marshall, O'Toole, Gerstein, Murray & Borun 6300 Sears Tower 233 South Wacker Drive Chicago, IL 60606-6402 (US)
Priority Data:
60/075,508 23.02.1998 US
Title (EN) PHOSPHODIESTERASE 10
(FR) PHOSPHODIESTERASE 10
Abstract: front page image
(EN)The present invention provides novel human PDE10 polypeptides, polynucleotides encoding the polypeptides, expression constructs comprising the polynucleotides, host cells transformed with the expression constructs; methods for producing PDE10 polypeptides; antisense polynucleotides; and antibodies specifically immunoreactive with the PDE10 polypeptides. The invention further provides methods to identify binding partners of PDE10, and more particularly, binding partners that modulate PDE10 enzyme activity.
(FR)La présente invention concerne de nouveaux polypeptides humains PDE10, des polynucléotides codant pour ces polypeptides, des constructions d'expression renfermant ces polynucléotides, des cellules hôtes transformées au moyen des constructions d'expression; des techniques de fabrication de polypeptides PDE10, des polynucléotides antisens; et des anticorps spécifiquement immuno-réactifs avec les polypeptides PDE10. Cette invention concerne par ailleurs des techniques permettant d'identifier des partenaires de liaison des PDE10 et, plus particulièrement, de ceux d'entre eux qui modulent l'activité enzymatique de PDE10.
Designated States: AL, AM, AT, AU, AZ, BA, BB, BG, BR, BY, CA, CH, CN, CU, CZ, DE, DK, EE, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MD, MG, MK, MN, MW, MX, NO, NZ, PL, PT, RO, RU, SD, SE, SG, SI, SK, SL, TJ, TM, TR, TT, UA, UG, UZ, VN, YU, ZW.
African Regional Intellectual Property Organization (GH, GM, KE, LS, MW, SD, SZ, UG, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, CH, CY, DE, DK, ES, FI, FR, GB, GR, IE, IT, LU, MC, NL, PT, SE)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)