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Machine translation
1. (WO1999042459) PROCESS FOR PRODUCING OPTICALLY ACTIVE CHROMENE DERIVATIVE
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/1999/042459    International Application No.:    PCT/JP1999/000650
Publication Date: 26.08.1999 International Filing Date: 16.02.1999
Chapter 2 Demand Filed:    21.06.1999    
IPC:
C07D 311/30 (2006.01), C07D 407/04 (2006.01)
Applicants: SHIONOGI & CO., LTD. [JP/JP]; 1-8, Doshomachi 3-chome Chuo-ku Osaka-shi Osaka 541-0045 (JP) (For All Designated States Except US).
KONOIKE, Toshiro [JP/JP]; (JP) (For US Only).
YORIFUJI, Tadahiko [JP/JP]; (JP) (For US Only).
SHINOMOTO, Shoji [JP/JP]; (JP) (For US Only).
IDE, Yutaka [JP/JP]; (JP) (For US Only).
OHYA, Takashi [JP/JP]; (JP) (For US Only).
MATSUMURA, Ken-ichi [JP/JP]; (JP) (For US Only)
Inventors: KONOIKE, Toshiro; (JP).
YORIFUJI, Tadahiko; (JP).
SHINOMOTO, Shoji; (JP).
IDE, Yutaka; (JP).
OHYA, Takashi; (JP).
MATSUMURA, Ken-ichi; (JP)
Agent: YAMAUCHI, Hideaki; Shionogi & Co., Ltd. Patent Dept. 12-4, Sagisu 5-chome Fukushima-ku, Osaka-shi Osaka 553-0002 (JP)
Priority Data:
10/35296 18.02.1998 JP
Title (EN) PROCESS FOR PRODUCING OPTICALLY ACTIVE CHROMENE DERIVATIVE
(FR) PROCEDE DE PRODUCTION D'UN DERIVE DE CHROMENE OPTIQUEMENT ACTIF
Abstract: front page image
(EN)A process for producing a compound represented by formula (II) (wherein R?1¿, R?2¿, R?3¿, and R?4¿ each independently represents hydrogen, alkyl, alkoxy, etc.; R?5¿ represents alkyl or alkoxyalkyl; A represents O or S; Ar represents aryl, etc.; * indicates the position of an asymmetric carbon atom and that the compound is the (R) or (S) isomer; and Q represents an optically active reagent), characterized by isolating the target compound as crystals from a solution or suspension containing a compound represented by formula (II) (wherein * indicates the position of an asymmetric carbon atom and that the compound is the (R) or (S) isomer or is a mixture of both, and the other symbols have the same meanings as the above).
(FR)L'invention concerne un procédé de production d'un composé représenté par la formule (II) (dans laquelle R?1¿, R?2¿, R?3¿ et R?4¿ sont chacun indépendamment hydrogène, alkyle, alkoxy, etc.; R?5¿ est alkyle ou alkoxyalkyle; A est O ou S; Ar est aryle, etc.; * indique la position d'un atome de carbone asymétrique et que le composé est l'isomère (R) ou (S); et Q est un réactif optiquement actif). Le procédé est caractérisé par l'isolement du composé cible comme cristaux à partir d'une solution ou d'une suspension contenant un composé représenté par la formule (II) (dans laquelle * indique la position d'un atome de carbone asymétrique et que le composé est l'isomère (R) ou (S), ou un mélange des deux, les autres symboles ayant les mêmes significations que celles mentionnées plus haut).
Designated States: AL, AM, AT, AU, AZ, BA, BB, BG, BR, BY, CA, CH, CN, CU, CZ, DE, DK, EE, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MD, MG, MK, MN, MW, MX, NO, NZ, PL, PT, RO, RU, SD, SE, SG, SI, SK, SL, TJ, TM, TR, TT, UA, UG, US, UZ, VN, YU, ZW.
African Regional Intellectual Property Organization (GH, GM, KE, LS, MW, SD, SZ, UG, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, CH, CY, DE, DK, ES, FI, FR, GB, GR, IE, IT, LU, MC, NL, PT, SE)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GW, ML, MR, NE, SN, TD, TG).
Publication Language: Japanese (JA)
Filing Language: Japanese (JA)