WIPO logo
Mobile | Deutsch | Español | Français | 日本語 | 한국어 | Português | Русский | 中文 | العربية |
PATENTSCOPE

Search International and National Patent Collections
World Intellectual Property Organization
Search
 
Browse
 
Translate
 
Options
 
News
 
Login
 
Help
 
Machine translation
1. (WO1999042075) ANTIBODIES AGAINST HUMAN CD40
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/1999/042075    International Application No.:    PCT/US1999/002949
Publication Date: 26.08.1999 International Filing Date: 10.02.1999
Chapter 2 Demand Filed:    02.09.1999    
IPC:
A61K 38/00 (2006.01), C07K 16/28 (2006.01)
Applicants: BRISTOL-MYERS SQUIBB COMPANY [US/US]; P.O. Box 4000 Princeton, NJ 08543-4000 (US)
Inventors: ARUFFO, Alejandro, A.; (US).
HOLLENBAUGH, Diane; (US).
SIADAK, Anthony, W.; (US).
BERRY, Karen, K.; (US).
HARRIS, Linda, J.; (US).
THORNE, Barbara, A.; (US).
BAJORATH, Jurgen; (US).
WU, Herren; (US).
HUSE, William, D.; (US).
WATKINS, Jeffry, D.; (US)
Agent: KLEIN, Christopher, A.; Bristol-Myers Squibb Company P.O. Box 4000 Princeton, NJ 08543-4000 (US)
Priority Data:
09/026,291 19.02.1998 US
Title (EN) ANTIBODIES AGAINST HUMAN CD40
(FR) ANTICORPS CONTRE LE CD40 HUMAIN
Abstract: front page image
(EN)The Applicants have discovered novel chimeric and humanized anti-human CD40 antibodies which block the interaction between gp39 and CD40. The anti-CD40 antibodies of the present invention are effective in modulating humoral immune responses against T cell-dependent antigens, collagen induced arthritis, and skin transplantation, and are also useful for their anti-inflammatory properties.
(FR)L'invention porte sur de nouveaux anticorps chimères et humanisés anti CD40 qui bloquent l'interaction entre le gp39 et le CD40 et s'avèrent efficaces: pour moduler la réponse immunitaire humorale contre les antigènes dépendants des cellules T, contre l'arthrite induite par le collagène, lors des transplantations de la peau, et en raison de leurs propriétés anti-inflammatoires.
Designated States: AL, AM, AT, AU, AZ, BA, BB, BG, BR, BY, CA, CH, CN, CU, CZ, DE, DK, EE, ES, FI, GB, GE, GH, GM, HU, ID, IL, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MD, MG, MK, MN, MW, MX, NO, NZ, PL, PT, RO, RU, SD, SE, SG, SI, SK, SL, TJ, TM, TR, TT, UA, UG, UZ, VN, YU, ZW.
African Regional Intellectual Property Organization (GH, GM, KE, LS, MW, SD, SZ, UG, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, CH, CY, DE, DK, ES, FI, FR, GB, GR, IE, IT, LU, MC, NL, PT, SE)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)