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Machine translation
1. (WO1999041614) METHOD FOR DETECTING INTIMIN PRODUCING MICROORGANISMS
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/1999/041614    International Application No.:    PCT/GB1999/000467
Publication Date: 19.08.1999 International Filing Date: 16.02.1999
Chapter 2 Demand Filed:    14.09.1999    
IPC:
A61K 38/00 (2006.01), A61K 39/00 (2006.01), C07K 14/24 (2006.01), C07K 14/245 (2006.01), C07K 16/12 (2006.01), C12Q 1/04 (2006.01), G01N 33/569 (2006.01)
Applicants: IMPERIAL COLLEGE OF SCIENCE, TECHNOLOGY AND MEDICINE [GB/GB]; London SW7 2AZ (GB) (For All Designated States Except US).
BATCHELOR, Miranda [GB/GB]; (GB) (For US Only).
DOUGAN, Gordon [GB/GB]; (GB) (For US Only).
FRANKEL, Gad [IL/GB]; (GB) (For US Only)
Inventors: BATCHELOR, Miranda; (GB).
DOUGAN, Gordon; (GB).
FRANKEL, Gad; (GB)
Agent: CHAPMAN, Paul, William; Kilburn & Strode 20 Red Lion Street London WC1R 4PJ (GB)
Priority Data:
9803322.8 16.02.1998 GB
Title (EN) METHOD FOR DETECTING INTIMIN PRODUCING MICROORGANISMS
(FR) PROCEDES
Abstract: front page image
(EN)Methods of detecting and/or diagnosing intimin-expressing microorganisms such as enteropathogenic $i(Escherichia coli) (EPEC), enterohemorrhagic $i(E. coli), $i(C. rodentium) and/or RDEC-1, as well as kits for use in such methods are provided. In particular, methods based antisera raised against conserved regions are described, as well as polypeptide regions useful in the production of antisera. Vaccines based on such peptides are also described herein. In addition, methods of typing/classification of such bacteria are also described herein. Finally, methods for the isolation of intimin-expressing microorganisms are also provided.
(FR)La présente invention concerne des procédés permettant de détecter et/ou de diagnostiquer la présence de micro-organismes exprimant l'intimine, tels que $i(l'Escherichia coli) entérophatogène, l'$i(Escherichia coli) entérohémorragique, le $i(C. rodentium) et/ou le RDEC-1, ainsi que des trousses à utiliser avec ces procédés. L'invention se rapporte en particulier à des antisérums dirigés contre des régions conservées obtenus selon les procédés de l'invention, et à des régions polypeptidiques utilisées dans la production des antisérums. L'invention concerne également des vaccins basés sur ces peptides, ainsi que des procédés de typage/classification des bactéries précitées. L'invention se rapporte enfin à des procédés permettant d'isoler les micro-organismes exprimant l'intimine.
Designated States: AL, AM, AT, AU, AZ, BA, BB, BG, BR, BY, CA, CH, CN, CU, CZ, DE, DK, EE, ES, FI, GB, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MD, MG, MK, MN, MW, MX, NO, NZ, PL, PT, RO, RU, SD, SE, SG, SI, SK, SL, TJ, TM, TR, TT, UA, UG, US, UZ, VN, YU, ZW.
African Regional Intellectual Property Organization (GH, GM, KE, LS, MW, SD, SZ, UG, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, CH, CY, DE, DK, ES, FI, FR, GB, GR, IE, IT, LU, MC, NL, PT, SE)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)