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Machine translation
1. (WO1999041372) POTASSIUM CHANNEL POLYPEPTIDE
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/1999/041372    International Application No.:    PCT/GB1999/000423
Publication Date: 19.08.1999 International Filing Date: 11.02.1999
Chapter 2 Demand Filed:    23.08.1999    
IPC:
A61K 38/00 (2006.01), A61K 48/00 (2006.01), C07K 14/705 (2006.01)
Applicants: ASTRAZENECA UK LIMITED [GB/GB]; 15 Stanhope Gate London W1Y 6LN (GB)
Inventors: AIYAR, Jayashree; (US).
LOGSDON, Naomi, Jean; (US).
ZHOU, Jianming; (US)
Agent: PHILLIPS, Neil, Godfrey, Alasdair; AstraZeneca UK Limited Global Intellectual Property Mereside, Alderley Park Macclesfield, Cheshire SK10 4TG (GB)
Priority Data:
60/074,999 17.02.1998 US
Title (EN) POTASSIUM CHANNEL POLYPEPTIDE
(FR) POLYPEPTIDE DE CANAL DE POTASSIUM
Abstract: front page image
(EN)A human potassium channel polypeptide is described which is tissue-specific to the human brain. A full length cDNA which encodes the potassium channel polypeptide is disclosed as well as the interior structural region and the amino acid residue sequence of the human brain potassium channel biomolecule. Methods are provided to identify compounds that modulate the pharmacological activity of the potassium channel biomolecule and hence regulate brain potassium channel biological activity.
(FR)L'invention concerne un nouveau polypeptide de canal de potassium humain, spécifique du tissu du cerveau humain. L'invention concerne également un ADN complémentaire pleine longueur, qui code pour le nouveau polypeptide de canal de potassium ainsi que pour la région structurale intérieure, et pour la séquence résiduelle d'acide aminé de la biomolécule de canal de potassium du cerveau humain. Ces techniques permettent d'identifier des composés qui modulent l'activité pharmacologique de ladite biomolécule et régulent ainsi l'activité biologique du canal de potassium du cerveau humain.
Designated States: AL, AM, AT, AU, AZ, BA, BB, BG, BR, BY, CA, CH, CN, CU, CZ, DE, DK, EE, ES, FI, GB, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MD, MG, MK, MN, MW, MX, NO, NZ, PL, PT, RO, RU, SD, SE, SG, SI, SK, SL, TJ, TM, TR, TT, UA, UG, UZ, VN, YU, ZW.
African Regional Intellectual Property Organization (GH, GM, KE, LS, MW, SD, SZ, UG, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, CH, CY, DE, DK, ES, FI, FR, GB, GR, IE, IT, LU, MC, NL, PT, SE)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)